Mycobacterium avium infection in Portugal

• Type: Article in International Scientific Journal
• Date: 2017-02

Authors

Duarte R (Author) FMUP

Journal

Title: The International Journal of Tuberculosis and Lung Disease

Vol. 21

Pages: 218-222

ISSN: 1027-3719

Publisher: International Union Against Tuberculosis And Lung Disease

Indexing

ISI Web of Knowledge - 8 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-00M-HTM

DOI: 10.5588/ijtld.16.0002

Abstract (EN): BACKGROUND: Although the incidence rates of nontuberculous mycobacteria (NTM) have been increasing in many countries, the basic epidemiology of NTM remains to be fully understood. OBJECTIVE : To assess the incidence, clinical relevance and geographical distribution of NTM disease in Portugal and to identify demographic and clinical characteristics associated with Mycobacterium avium complex (MAC) disease. METHODS : Information stored in an electronic database of all NTM cases reported over an 11-year period was retrospectively reviewed. Significant demographic and clinical characteristics of MAC disease (vs. having any other NTM disease) were determined using multiple logistic regression models. RESULT S : We identified 632 patients, mostly male, native Portuguese, with pulmonary disease, predominantly from Lisbon and Porto. The annual incidence of NTM disease was 0.54 per 100 000 population. The annual number of NTM cases increased throughout the study period. MAC was most frequently isolated. MAC disease was positively (and significantly) associated with being female, age .45 years and human immunodeficiency virus infection. CONCLUS IONS : The increasing incidence ofNTMover the study period emphasises the importance of NTM as a public health issue. This study provides important information for health care professionals and a basis for further study of NTM in Portugal. © 2017 Chipinduro et al.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5