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Sources and biological activities of marine sulfated steroids

Title
Sources and biological activities of marine sulfated steroids
Type
Another Publication in an International Scientific Journal
Year
2018
Authors
Carvalhal, F
(Author)
Other
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Marta Correia da Silva
(Author)
FFUP
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Emilia Sousa
(Author)
FFUP
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Pinto, M
(Author)
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Kijjoa, A
(Author)
Other
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Journal
Vol. 61
Pages: T211-T231
ISSN: 0952-5041
Publisher: BioScientifica Ltd.
Other information
Authenticus ID: P-00N-GBK
Abstract (EN): Marine environment is rich in structurally unique molecules and can be an inspiring source of novel drugs. Currently, six marine-derived drugs are in the market with FDA approval and several more are in the clinical pipeline. Structurally diverse and complex secondary metabolites have been isolated from the marine world and these include sulfated steroids. Biological activities of nearly 150 marine sulfated steroids reported from 1978 to 2017 are compiled and described, namely antimicrobial, antitumor, cardiovascular and antifouling activities. Structure-activity relationship for each activity is discussed.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 21
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