Magnetoliposomes based on nickel/silica core/shell nanoparticles: Synthesis and characterization

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Rodrigues, ARO (Author) Other; Gomes, IT (Author) Other; Almeida, BG (Author) Other; araujo, j. p. (Author) FCUP; Castanheira, EMS (Author) Other; Coutinho, PJG (Author) Other

Journal

Title: Materials Chemistry and Physics

Vol. 148

Pages: 978-987

ISSN: 0254-0584

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 10 Citations

Scopus - 13 Citations

Other information

Authenticus ID: P-009-YCN

DOI: 10.1016/j.matchemphys.2014.09.008

Abstract (EN): In the present work, nickel magnetic nanoparticles with diameters lower than 100 nm, with and without silica shell, were synthesized by microheterogeneous templating. The magnetic properties of the nanoparticles show a typical ferromagnetic behavior with a coercive field of 80 Oe. Dry magnetoliposomes (DMLs) with diameter between 58 nm and 76 nm were obtained from the synthesis of nanoparticles in the presence of a lipid or surfactant layer, and aqueous magnetoliposomes (AMLs) were obtained by encapsulation of the nanoparticles in liposomes. FRET (Forster resonance energy transfer) experiments were performed to study the non-specific interactions between aqueous magnetoliposomes and giant unilamellar vesicles (GUVs), as models of cell membranes. It was possible to detect membrane fusion between GUVs and AMLs containing both NBD-C-6-HPC (donor) and the dye Nile Red (acceptor).

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10