An adaptive approach to Target Controlled Infusion

• Type: Article in International Conference Proceedings Book
• Date: 2009

Authors

Silva, MM (Author) Other; Alonso, H (Author) Other; Lemos, JM (Author) Other; Mendonca, T (Author) FCUP

Conference proceedings International

Title: 2009 European Control Conference, ECC 2009

Pages: 418-423

2009 10th European Control Conference, ECC 2009

23 August 2009 through 26 August 2009

Indexing

Scopus - 2 Citations

Other information

Authenticus ID: P-00A-C1P

Abstract (EN): This paper proposes an adaptive approach to improve the performance of Target Controlled Infusion (TCI) based strategies. The method determines an adequate drug dose profile that drives the drug effect on the individual patient to a desired target in a prespecified period of time. It combines an optimal variance constrained drug dose design with a hybrid identification of the individual patient dynamics. Simulation results based on a bank of one hundred neuromuscular blockade patient models are presented to demonstrate the feasibility of the proposed method. © 2009 EUCA.

Language: English

Type (Professor's evaluation): Scientific