beta-Cyclodextrin carbon nanotube-enhanced sensor for ciprofloxacin detection

• Type: Article in International Scientific Journal
• Date: 2017

Authors

Garrido, JMPJ (Author) Other; Melle Franco, M (Author) Other; Strutynski, K (Author) Other; Fernanda Borges (Author) FCUP; Brett, CMA (Author) Other; Garrido, EMPJ (Author) Other

Journal

Title: Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

Vol. 52

Pages: 313-319

ISSN: 1093-4529

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 39 Citations

Scopus - 45 Citations

Other information

Authenticus ID: P-00M-JH2

DOI: 10.1080/10934529.2016.1258864

Abstract (EN): A simple and expedite electrochemical methodology was developed for the determination of ciprofloxacin, based on a glassy carbon (GC) electrode modified by a combination of multi-walled carbon nanotubes (MWCNT) with -cyclodextrin (-CD) incorporated in a polyaniline film. The combined use of -CD and MWCNT in the electrochemical sensor leads to a significant signal improvement. The -CD/MWCNT modified GC electrode exhibited efficient electrocatalytic behavior in the oxidation of ciprofloxacin with relatively high sensitivity, stability and lifetime. Molecular modeling studies showed that ciprofloxacin binds preferably to -CD rather than to CNT edges, leading to an improved sensitivity of the sensor. Under optimized conditions, a linear calibration curve was obtained for ciprofloxacin in the concentration range 10-80 mu M with a detection limit of 50nM. The analytical performance of this sensor was evaluated for the detection of ciprofloxacin in a wastewater treatment plant effluent.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7