Microspheres based on hydroxyapatite nanoparticles aggregates for bone regeneration

• Type: Article in International Conference Proceedings Book
• Date: 2007

Authors

Mateus, AYP (Author) Other; Ferraz, MP (Author) Other; Fernando Mendes Monteiro (Author) FEUP

Conference proceedings International

Title: Bioceramics, Vol 19, Pts 1 and 2

Pages: 243-246

19th International Symposium on Ceramics in Medicine

Chengdu, PEOPLES R CHINA, OCT 10-13, 2006

Indexing

ISI Web of Knowledge - 20 Citations

Scopus - 22 Citations

Other information

Authenticus ID: P-004-CKS

Abstract (EN): This study concerns the preparation and characterisation of microspheres associating alginate and two different types of hydroxyapatite (HA), which are intended to be used as drug delivery systems and bone regeneration matrices. Hydroxyapatite nanoparticles (HA-1 and HA-2) were prepared using a chemical precipitation synthesis based on H3PO4, Ca(OH)2 and a surfactant, SIDS (sodium dodecylsulphate), as starting reagents. These two powders of nanoHA and alginate were used to prepare two different types of microspheres. Both powders and microspheres were characterised using FTIR, TEM, SEM, mercury porosimetry analysis and X-ray diffraction Results show that pure hydroxyapatite (HA) and mixtures of HA/beta-TCP in the nanometre range were obtained from both HA syntheses. Microspheres with different characteristics were obtained from these two types of hydroxyapatite.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4