Monoamines and cortisol as potential mediators of the relationship between exercise and depressive symptoms

• Type: Article in International Scientific Journal
• Date: 2017

Authors

Carneiro, LSF (Author) Other; Mota, MP (Author) Other; vieira-coelho, ma (Author) FMUP; Rita C. Alves (Author) FFUP; Antonio Manuel Fonseca (Author) FADEUP; Vasconcelos Raposo, J (Author) Other

Journal

Title: European Archives of Psychiatry and Clinical Neuroscience

Vol. 267

Pages: 117-121

ISSN: 0940-1334

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 19 Citations

Scopus - 24 Citations

Other information

Authenticus ID: P-00K-QKJ

DOI: 10.1007/s00406-016-0719-0

Abstract (EN): A randomized controlled trial was conducted to assess the effects of exercise plus pharmacotherapy on monoamine neurotransmitters (dopamine, noradrenaline, adrenaline, serotonin) and cortisol levels. A total of 26 women with clinical depression were randomly assigned to one of the two groups: aerobic exercise plus pharmacotherapy or only pharmacotherapy. The exercise program consisted of aerobic exercise, 45-50 min/session, three times/week, for 16 weeks. The biological parameters were measured before and after the exercise program. Adding exercise to pharmacotherapy had no additional effects on monoamines and cortisol plasma levels. These data are preliminary outcomes from a small sample and should be replicated.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5