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Outcome of 88 pregnancies with absent or reversed end-diastolic blood flow (ARED flow) in the umbilical arteries

Title
Outcome of 88 pregnancies with absent or reversed end-diastolic blood flow (ARED flow) in the umbilical arteries
Type
Article in International Scientific Journal
Year
1998
Authors
Montenegro N
(Author)
FMUP
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Santos, F
(Author)
Other
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Tavares, E
(Author)
Other
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matias, a
(Author)
Other
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Barros H
(Author)
FMUP
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Leite, LP
(Author)
Other
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Journal
Vol. 79
Pages: 43-46
ISSN: 0301-2115
Publisher: Elsevier
Other information
Authenticus ID: P-001-7HV
Abstract (EN): Objectives: to investigate both perinatal and postneonatal morbidity and mortality in fetuses with absent or reversed end-diastolic flow (ARED flow) in the umbilical artery. Study design: A 5 year prospective follow-up of 88 fetuses with ARED flow. Results: Sixteen stillbirths, 16 neonatal deaths, six postneonatal deaths and one death at 2 years of age were noted. Out of the 42 fetuses born alive, 36 showed a normal neurological development whereas six were mentally handicapped. Adverse prognosis was more frequently found in the group with absent end-diastolic flow at first examination and then reversed flow until delivery, compared to the groups of always absent or always reversed end-diastolic flows. Conclusions: Prompt delivery is recommended in these high-risk pregnancies in order to prevent long-term sequelae, obviously depending on the local limits of viability. Further studies appropriately designed for assessing long-term neurodevelopment of fetuses with ARED flow, although demanding, are mandatory. (C) 1998 Elsevier Science Ireland Ltd.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 4
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