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Release Studies of Thymol and p-Cymene from Polylactide Microcapsules

Title
Release Studies of Thymol and p-Cymene from Polylactide Microcapsules
Type
Article in International Scientific Journal
Year
2012
Authors
Isabel M. Martins
(Author)
Other
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Rodrigues, SN
(Author)
Other
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Barreiro, MF
(Author)
Other
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Alírio Rodrigues
(Author)
FEUP
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Journal
Vol. 51
Pages: 11565-11571
ISSN: 0888-5885
Other information
Authenticus ID: P-002-5JD
Abstract (EN): The objective of this work is to access the release behavior of thymol and p-cymene used as model core materials with PLA microcapsules. The microcapsules were obtained by a coacervation process developed in a previous work and present a spherical shape with mean particle size of 25 and 37 mu m for thymol and p-cymene, respectively. The results have shown that the release of thymol and p-cymene is faster in the first hour keeping almost constant in the subsequent days. The diffusion coefficient in the first hour of release was 1.99 X 10(-16) m(2)/s for thymol and 4.34 X 10(-16) m(2)/s for p-cymene. However, the diffusion was slower if considering a period of 5 days being the diffusion coefficients of 3.34 X 10(-19) m(2)/s for thymol and 3.45 X 10(-18) m(2)/s for cymene.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 7
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