Adhesion and proliferation of human osteoblastic cells seeded on injectable hydroxyapatite microspheres

• Type: Article in International Scientific Journal
• Date: 2004

Authors

C. C. Barrias (Author) Other; C. C. Ribeiro (Author) Other; Mário Adolfo Barbosa (Author) FEUP

Journal

Title: Bioceramics

Vol. 254-2

Pages: 877-880

Indexing

ISI Web of Knowledge - 10 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-000-CBR

DOI: 10.4028/www.scientific.net/KEM.254-256.877

Abstract (EN): In the present work, the interaction of human osteoblast-like MG63 cells with novel hydroxyapatite (HAp) microspheres was investigated. Cells were seeded on the microspheres and incubated for up to 7 days. The cell-material constructs were visualised by scanning electron microscopy and confocal laser scanning microscopy, and the rate of cell proliferation was estimated using the Neutral Red assay. The results showed that osteoblastic cells were able to adhere and proliferate on the HAp microspheres, which are intended to be used as injectable support-materials for bone regeneration.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4