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Heart rate and ventricular repolarization variabilities interactions modification by microgravity simulation during head-down bed rest test

Title
Heart rate and ventricular repolarization variabilities interactions modification by microgravity simulation during head-down bed rest test
Type
Article in International Conference Proceedings Book
Year
2013
Authors
Bolea, J
(Author)
Other
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Laguna, P
(Author)
Other
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Caiani, EG
(Author)
Other
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Conference proceedings International
Pages: 552-553
26th IEEE International Symposium on Computer-Based Medical Systems (CBMS)
Porto, PORTUGAL, JUN 20-22, 2013
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Authenticus ID: P-008-HZG
Abstract (EN): Features extracted from heart rate variability (HRV) have allowed to classify several cardiac disorders. In this work, the linear relationship between HRV and ventricular repolarization variability is studied as a possible feature for stratifying risk of cardiac arrhythmias under weightlessness conditions. Three VR beat-to-beat indexes extracted from ECG signals as QT, QT(p) (QRS onset to T wave peak) and T-pe (peak to end of T wave) were measured. ARARX modeling was used to estimate the VR variability fraction driven by HRV. Head down bed rest as microgravity Earth-based test increased the linear dependency of VR variability driven by HRV. Furthermore, in a pairwise comparison between PRE and POST conditions showed significant differences (p-values < 0.05) for T-pe variability contents. These results evidence a reduced recovery capacity for the T-pe repolarization variability to restore its linear dependency values to HR in the first moments at the end of BR.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 2
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