Angiogenesis and breast cancer

• Type: Another Publication in an International Scientific Journal
• Date: 2010

Authors

Fernando Schmitt (Author) FMUP; Longatto Filho, A (Author) Other; Lopes, JM (Author) FMUP

Journal

Title: Journal of Oncology

Vol. 2010

Pages: 1-7

ISSN: 1687-8450

Publisher: Hindawi

Indexing

Scopus - 93 Citations

Other information

Authenticus ID: P-007-W7C

DOI: 10.1155/2010/576384

Abstract (EN): Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer. Copyright © 2010 Adhemar Longatto Filho et al.

Language: English

Type (Professor's evaluation): Scientific