Canine carcinogenesis in translational cancer research

• Type: Chapter or Part of a Book
• Date: 2012

Authors

Pinho, SS (Author) Other; Carvalho, S (Author) Other; Cabral, J (Author) Other; Celso Reis (Author) ICBAS; Gartner, F (Author) Other

Book

Title: Canine Behavior, Classification and Diseases

Pages: 57-74

ISBN: 9781620813041

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-008-YPY

Abstract (EN): The biological complexity of human cancer has stimulated the development of complex experimental systems that could resemble in a natural and spontaneous manner the physiopathological aspects of cancer biology. Companion animals display many aspects of the complexity of human cancer filling the gap between in vitro and in vivo studies. Spontaneous tumors in dogs share a wide variety of epidemiological, biological and clinical features with human cancer, which makes this a valid tumor model system available for studying cancer biology in oncology research. In this review we summarize the importance of naturally occurring canine tumors as a valuable model for studying many aspects of human cancer, as well as the potential use of this animal model for the development of new cancer treatments.

Language: English

Type (Professor's evaluation): Scientific