Adenosine receptor interactions in the hippocampus

• Type: Article in International Scientific Journal
• Date: 2001

Authors

Ribeiro, JA (Author) Other; Cunha Reis, D (Author) Other; Lopes, LV (Author) Other; Coelho, JE (Author) Other; Costenla, AR (Author) Other; Paulo Correia de Sá (Author) ICBAS; Cunha, RA (Author) Other; de Mendonca, A (Author) Other; Sebastiao, AM (Author) Other

Journal

Title: Drug Development Research

Vol. 52

Pages: 337-345

ISSN: 0272-4391

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-000-X0S

DOI: 10.1002/ddr.1132

Abstract (EN): Adenosine receptors are involved in interactions with receptors for other neurotransmitters and/or neuromodulators. This opens novel possibilities for the action of this nucleoside. Either through direct receptor-receptor modulation or beyond the receptor level (PKA, PKC, or calcium channels), it appears that to protect the cells from insult adenosine moves around to use as many several receptor systems as possible, namely, receptors for neuropeptides (CGRP and VIP), ionotropic (NMDA) and metabotropic (mGlur I and III) glutamate receptors, GABA, and nicotinic autofacilitatory, muscarinic, and dopamine receptors. With these, adenosine might synchronize or desynchronize synaptic transmission in order to fine-tune the nervous system. Drug Dev. Res. 52:337-345, 2001, (C) 2001 Wiley-Liss, Inc.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9