COLUMNAR-CELL CARCINOMA - ANOTHER VARIANT OF POORLY DIFFERENTIATED CARCINOMA OF THE THYROID

• Type: Article in International Scientific Journal
• Date: 1988

Authors

Sobrinho Simoes, M (Author) FMUP; NESLAND, JM (Author) Other; JOHANNESSEN, JV (Author) Other

Journal

Title: American Journal of Clinical Pathology

Vol. 89

Pages: 264-267

ISSN: 0002-9173

Publisher: Oxford University Press

Indexing

ISI Web of Knowledge - 85 Citations

Scopus - 74 Citations

Other information

Authenticus ID: P-001-TJ9

Abstract (EN): An unusual case of poorly differentiated carcinoma of the thyroid is reported. The tumor occurred in a 60-year-old man, who died with widespread metastases 5.5 years after primary treatment. The unencapsulated tumor measured 8 x 5 x 9.5 cm and was composed of columnar cells. Two or three mitotic figures per 10 high-power fields were present. The cells were thyroglobulin positive and not stained for calcitonin and carcinoembryonic antigen (CEA). The light microscopic appearance was similar to that of a metastasis from a carcinoma of the bowel. The authors conclude that columnar cell carcinoma is a separate type of thyroid carcinoma that shares the clinical properties of both follicular and papillary carcinoma and carries a poor prognosis. However, for practical purposes, the authors think that the tumor should be included in the category of poorly differentiated thyroid carcinomas together with the so-called insular carcinomas, mucoepidermoid carcinomas, and mucinous carcinomas.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4