Schistosoma haematobium and Schistosomiasis mansoni: Production of an estradiol-related compound detected by elisa

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Botelho, MC (Author) Other; Crespo, M (Author) Other; Almeida, A (Author) Other; Vieira, P (Author) Other; Delgado, ML (Author) Other; Araujo, L (Author) Other; Machado JC (Author) FMUP; Correia da Costa, JMC (Author) Other

Journal

Title: Experimental Parasitology

Vol. 122

Pages: 250-253

ISSN: 0014-4894

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 25 Citations

Scopus - 25 Citations

Other information

Authenticus ID: P-003-HR1

DOI: 10.1016/j.exppara.2009.04.001

Abstract (EN): Estradiol is a steroid hormone secreted principally by the ovarian follicles in vertebrate animals. We have identified the production of an estradiol-related molecule in the trematodes Schistosoma haematobium and Schistosomiasis mansoni. We show in this work that this molecule related to estradiol is present in schistosome worm extracts. The detection method ELISA specific for estradiol, revealed the expression of this estradiol-related molecule in schistosome worm extracts, but not in Fasciola hepatica worm extracts. Our results demonstrate for the first time the production of an estradiol-related compound by a human parasite of the genus Schistosoma.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4