Evolution of familial aggregation of blood pressure over 17 years in children and young adults [Agregation familiale de la pression arterielle de l'enfance a l'age adulte apres un suivi de 17 ans]

• Type: Article in International Scientific Journal
• Date: 1998

Authors

Macedo, ME (Author) Other; Pinto, AT (Author) Other; Pizarro, M (Author) Other; Marujo, C (Author) Other; Costa-Pereira A (Author) FMUP; De Falcao Freitas, A (Author) Other

Journal

Title: Archives des Maladies du Coeur et des Vaisseaux

Vol. 91

Pages: 1087-1089

ISSN: 0003-9683

Publisher: Editions J B Bailliere

Indexing

Scopus - 2 Citations

Other information

Authenticus ID: P-007-84N

Abstract (EN): Familial aggregation of blood pressure is well known although its causes remain controversial. The aim of the present study is to evaluate the presence of a familial aggregation for blood pressure and body mass index over a 17-year period, in order to evaluate the importance of a primary prevention strategy beginning in familial environment. Design and methods: A longitudinal cohort study was constructed from two cross-sectional surveys 17 years apart: 1 032 individuals, of both sexes, aged 5 to 24 years were seen in the initial study, and their parents whenever possible. Correlation coefficients and stepwise regression analysis were used to analyse the relationship between parents and children. Results: The correlation between parents' and childrens; BP are: systolic BP-0.34 (p < 0.01) and diastolic BP 0.19 (0.05); and for the anthropometric variables are: height-0.29 (0.01); weight-0.41 (p < 0.01); ponderal index-0.21 (p < 0.05) ; tricipt skinfold- 0.21 (p < 0.05). All the coefficients are statistically significative. The variance of children's SBP and DBP explained through a stepwise regression analysis was 47 %. The children's weight, skinfold, ponderal index, and parents' SBP and DBP were accepted by the model. Conclusion: The relation between BP and obesity variables suggest that a large proportion of familial aggregation for BP may be explained by aggregation for obesity, still after 17 years.

Language: French

Type (Professor's evaluation): Scientific