Adherens junctions as targets of microorganisms: A focus on Helicobacter pylori

• Type: Another Publication in an International Scientific Journal
• Date: 2013

Authors

Costa, AM (Author) Other; Marina Leite (Author) Other; Seruca, R (Author) FMUP; Figueiredo C (Author) FMUP

Journal

Title: FEBS Letters

Vol. 587

Pages: 259-265

ISSN: 0014-5793

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 26 Citations

Scopus - 26 Citations

Other information

Authenticus ID: P-002-14Q

DOI: 10.1016/j.febslet.2012.12.008

Abstract (EN): Mucosal epithelia are targeted by several microorganisms as a way of adhesion, internalization, and/or exploitation of the host properties to induce disease. Helicobacter pylori are worldwide prevalent bacteria that colonize the human stomach. Persistent infection of the gastric mucosa with H. pylori and concurrent chronic gastritis are risk factors for ulcer disease and gastric carcinoma. Therefore, interactions at the H. pylori-epithelial interface are important to understand the pathogenesis of these bacteria and the host responses that contribute to disease development. Here, we provide an overview of the interactions between microorganisms and the adherens junctions with an emphasis on H. pylori.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7