COORDINATION CHEMISTRY OF 7,9-DISUBSTITUTED 6-OXOPURINE METAL-COMPOUNDS .4. PLATINUM(II) COORDINATION AT N(1). MOLECULAR AND CRYSTAL-STRUCTURE OF [(ETHYLENEDIAMINE)BIS(7,9-DIMETHYLHYPOXANTHINE)PLATINUM(II)] HEXAFLUOROPHOSPHATE

• Type: Article in International Scientific Journal
• Date: 1982

Authors

KISTENMACHER, TJ (Author) Other; DECASTRO, B (Author) FCUP; WILKOWSKI, K (Author) Other; MARZILLI, LG (Author) Other

Journal

Title: Journal of Inorganic Biochemistry

Vol. 16

Pages: 33-46

ISSN: 0162-0134

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 19 Citations

Scopus - 10 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-005-6GM

DOI: 10.1016/s0162-0134(00)80243-3

Abstract (EN): The preparation and molecular and crystal structure of the complex [(ethylenediamine)bis(7,9,-dimethylhypoxanthine)platinum(II)] hexafluorophosphate, [Pt(C2H8N2)(C7H8N4O)2] (PF6)2, are reported. The complex crystallizes in the monoclinic system, space group C2/c, with a = 12.334(2)Å, b = 10.256(2)Å, c = 22.339(3)Å, ß = 101.31(1)°, V = 2771.0Å3, Z = 4, Dmeasd = 2.087(3) g cm-3, Dcalc = 2.094 g cm-3. Intensities for 3992 symmetry-averaged reflections were collected in the ¿-2o scan mode on an automated diffractometer employing graphite-monochromatized MoK¿ radiation. The structure was solved by standard heavy-atom Patterson and Fourier methods. Full matrix least-squares refinement led to a final R value of 0.051. Both the ethylenediamine chelate and the PF6 - anion are disordered. The primary coordination sphere about the Pt(II) center is approximately square planar with the bidentate ethylenediamine ligand and the N(1) atoms [Pt(II) - N(1) = 2.020(5)Å] of two 7,9-dimethylhypoxanthine bases (related by a crystallographic twofold axis of symmetry) occupying the four coordination sites. The exocyclic O(6) carbonyl oxygen atoms of the two 7,9-dimethylhypoxanthine ligands participate in intracomplex hydrogen bonding with the amino groups of the ethylenediamine chelate [N(ethylenediamine) ¿ O(6) = 2.89( )Å]. The observed Pt ¿ O(6) intramolecular distances of 3.074(6)Å are similar to those found in other Pt(II) N(1)-bound 6-oxopurine complexes and in several Pt(II) N(3)-bound cytosine systems. © 1982.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 14