Recent advances in salt-assisted LLE for analyzing biological samples

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Ines Maria Valente (Author) Other; Jose Antonio Rodrigues (Author) FCUP

Journal

Title: Bioanalysis

Vol. 7

Pages: 2187-2193

ISSN: 1757-6180

Publisher: Future Medicine Ltd.

Indexing

ISI Web of Knowledge - 21 Citations

Scopus - 22 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-00G-PT1

DOI: 10.4155/bio.15.142

Abstract (EN): Salt-assisted LLE (SALLE) has been attracting growing interest in bioanalysis. The technique is particularly advantageous due to its simple and fast experimental execution using conventional laboratory equipment. Besides, SALLE uses water-miscible organic solvents making the extracts readily compatible with various analytical separation and detection techniques. This article presents a brief overview of the extraction technique and its role in bioanalysis. Some of the most relevant achievements on SALLE application to biological samples are discussed - namely the study of the main extraction parameters, the combination with other extraction techniques and the instrumental analysis of the extracts. Developments on automation, miniaturization and microextraction for SALLE procedures are also discussed as a perspective for future applications even more attractive for the analysis of biological samples.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7