Risk factors for myocardial infarct: a case-control study in Oporto, Portugal [Factores de risco de enfarte do miocárdio: um estudo caso-controlo no Porto, Portugal.]

• Type: Article in International Scientific Journal
• Date: 1997

Authors

von Hafe, P (Author) Other; Lopes, C (Author) Other; Fernando, PB (Author) Other; Ramos, E (Author) Other; Andrade, MJ (Author) Other; Coelho, R (Author) Other; Maciel, MJ (Author) FMUP; Barros, H (Author) FMUP

Journal

Title: Revista Portuguesa de Cardiologia

Vol. 16 No. 6

Pages: 695-702, 664

ISSN: 0870-2551

Publisher: Sociedade Portuguesa De Cardiologia

Indexing

ISI Web of Knowledge

Scopus - 1 Citation

Other information

Authenticus ID: P-008-PQ6

Abstract (EN): A case-control study of coronary heart disease (CHD) was conducted in Oporto, Portugal. The cases series consisted of 100 consecutive patients with first time acute myocardial infarction who were admitted to the Coronary and Intermediate Care Units of a major teaching hospital. The community controls were 198 individuals without evidence of CHD by the Rose questionnaire and electrocardiography, selected by random digit dialing, with a participation rate of 70%. Data was collected by trained interviewers using a structured questionnaire and blood samples were obtained for selected laboratory data. The main analysis was made through unconditional logistic regression with calculations of odds ratios (OR). Age, OR: 1.5 (95% CI: 0.8-2.9), male gender, OR: 6.7 (3.6-12.3), family history of premature CHD, OR: 2.4 (1.4-4.3), diabetes, OR: 3.4 (1.6-7.4), antecedents of hypertension, OR:1.9 (1.1-3.1), history of high cholesterol levels, OR: 2.3 (1.4-3.9), high levels of physical activity, OR: 2.0 (0.9-4.1) and tobacco smoking, OR: 8.3 (3.8-18.5) were significant risk factors of acute myocardial infarction. After controlling for demographic variables and for the mutual confounding effects of the risk factors, the investigated factors that remained significantly associated with the risk of developing acute myocardial infarction were male gender, OR: 17.3 (4.8-62.3), family history of CHD, OR: 3.6 (1.4-9.6), diabetes, OR: 4.2 (1.0-18.1), high cholesterol levels OR: 2.7 (1.2-6.1) and smoking habits, OR: 7.7 (1.8-32.4). A negative association with high education levels was significant after controlling for all the variables, OR: 0.01 (0.01-0.5).

Language: Portuguese

Type (Professor's evaluation): Scientific