Experimental results of antigliadin antibodies detection using long period fiber grating

• Type: Article in International Conference Proceedings Book
• Date: 2008

Authors

Corres, JM (Author) Other; Matias, IR (Author) Other; Goicoechea, J (Author) Other; Arregui, FJ (Author) Other; Viegas, D (Author) Other; Araujo, FM (Author) Other; Santos, JL (Author) FCUP

Conference proceedings International

Title: 19TH INTERNATIONAL CONFERENCE ON OPTICAL FIBRE SENSORS, PTS 1 AND 2

19th International Conference on Optical Fibre Sensors

Perth, AUSTRALIA, APR 15-18, 2008

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 4 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-005-5PB

DOI: 10.1117/12.786076

Abstract (EN): In this work a new nano-biofilm is proposed for the detection of celiac disease (CD). A long-period fiber grating (LPFG) is used as a transducer and the surface of the fiber is coated with a precursor layer of SiO2-nanospheres using the electrostatic self-assembly technique (ESA). This layer has been designed in order to create a substrate of high porosity where the gliadins could be deposited. Under the presence of specific antibodies antigliadin antibodies (AGA) the refractive index of the overlay changes giving a detectable shift in the resonance wavelength of the LPFG. Concentrations as low as 5 ppm were detected.

Language: English

Type (Professor's evaluation): Scientific