Precipitation of Hydroxyapatite at 37 degrees C in a Meso Oscillatory Flow Reactor Operated in Batch at Constant Power Density

• Type: Article in International Scientific Journal
• Date: 2013

Authors

Filipa Castro (Author) FEUP; António Ferreira (Author) FEUP; Fernando Rocha (Author) FEUP; António Vicente (Author) Other; José António Teixeira (Author) Other

Journal

Title: AICHE Journal

Vol. 59 No. 10

Pages: 4483-4493

ISSN: 0001-1541

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 13 Citations

Scopus - 14 Citations

Scientific classification

FOS: Engineering and technology > Chemical engineering

Associated Projects

UI0511 - PROJECTO ESTRATÉGICO - UI 511 - 2013-2014

Other information

Authenticus ID: P-008-GVA

DOI: 10.1002/aic.14193

Abstract (EN): A meso oscillatory flow reactor (meso-OFR) was successfully applied for the precipitation of hydroxyapatite (HAp) nanoparticles. Mixing efficiency of the mesoreactor operated batchwise in a vertical tube was evaluated at constant power density, by monitoring variation of hue values upon mixing both spatially and temporally. The best operating conditions for fast mixing and a more homogeneous reaction medium were verified for f=0.83 Hz and x(0)=4.5 mm. HAp precipitation was then carried out under these conditions at 37 degrees C for different mixing Ca/P molar ratios. HAp nanoparticles with a mean size (d(50)) of about 67 nm and a narrow size distribution were obtained. Furthermore, the obtained results show the advantages of the meso-OFR over a stirred tank batch reactor due to the production, about four times faster, of smaller and more uniform HAp nanoparticles. (c) 2013 American Institute of Chemical Engineers AIChE J, 59: 4483-4493, 2013

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11