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Phase transition in tumor growth: I avascular development

Title
Phase transition in tumor growth: I avascular development
Type
Article in International Scientific Journal
Year
2013
Authors
Izquierdo Kulich, E
(Author)
Other
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Rebelo, I
(Author)
FFUP
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Tejera, E
(Author)
Other
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Nieto Villar, JM
(Author)
Other
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Journal
Vol. 392
Pages: 6616-6623
ISSN: 0378-4371
Publisher: Elsevier
Scientific classification
FOS: Natural sciences > Physical sciences
Other information
Authenticus ID: P-008-ES9
Abstract (EN): We propose a mechanism for avascular tumor growth based on a simple chemical network. This model presents a logistic behavior and shows a "second order" phase transition. We prove the fractal origin of the empirical logistics and Gompertz constant and its relation to mitosis and apoptosis rate. Finally, the thermodynamics framework developed demonstrates the entropy production rate as a Lyapunov function during avascular tumor growth.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
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