Silicon and iron levels in tissues of animals treated with a "ferrimagnetic ceramic" with oncotherapeutic potential (anti-tumor) value

• Type: Article in International Scientific Journal
• Date: 2002

Authors

Almedia, T (Author) Other; Soares, ME (Author) Other; Cavalheiro, J (Author) Other; Bastos, MD (Author) FFUP

Journal

Title: Journal of Trace Elements in Medicine and Biology

Vol. 16

Pages: 255-259

ISSN: 0946-672X

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 3 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-000-RHE

DOI: 10.1016/s0946-672x(02)80054-2

Abstract (EN): The stability in a biological environment of an injectable cement with oncotherapeutic potential - consisting of a glass powder of SiO2 (35.6%), CaO (42.4%), P2O5 (17%), Na2O (5%) and 30% of its weight of Fe3O4 dissolved in (NH4)(2)HPO4 plus NH4H2PO4 - was evaluated referring to the release of silicon and iron. The experimental model was the rat, and organs (Liver, kidney, spleen, lung, heart, and brain) of the implanted and control animals-were collected for quantification of these elements by electrothermal atomization atomic absorption spectrometry methods. In most of the analysed organs no significant difference in the contents of silicon and iron between the implanted and the control animals was found.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5