Presynaptic adenosine and P2Y receptors

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Goncalves, J (Author) FFUP

Journal

Title: Handbook of Experimental Pharmacology

Vol. 135

Pages: 339-372

ISSN: 0171-2004

Publisher: Springer Nature

Indexing

ISI Web of Knowledge

Scopus - 18 Citations

Other information

Authenticus ID: P-007-KF3

DOI: 10.1007/978-3-540-74805-2-11

Abstract (EN): Adenine-based purines, such as adenosine and ATP, are ubiquitous molecules that, in addition to their roles in metabolism, act as modulators of neurotransmitter release through activation of presynaptic P1 purinoceptors or adenosine receptors (activated by adenosine) and P2 receptors (activated by nucleotides). Of the latter, the P2Y receptors are G protein-coupled, whereas the P2X receptors are ligand-gated ion channels and not covered in this review. © 2008 Springer-Verlag Berlin Heidelberg.

Language: English

Type (Professor's evaluation): Scientific