Fetal and maternal placental growth factor in normal and preeclamptic pregnancy

• Type: Article in International Conference Proceedings Book
• Date: 2005

Authors

Catarino, C (Author) FFUP; Rebelo, I (Author) FFUP; Rocha, S (Author) Other; Belo, L (Author) FFUP; Castro, E (Author) Other; Patricio, B (Author) Other; Quintanilha, A (Author) Other; Santos Silva, A (Author) FFUP

Conference proceedings International

Title: Proceedings of the 7th World Congress of Perinatal Medicine

Pages: 247-251

7th World Congress of Perinatal Medicine

Zagreb, CROATIA, SEP 21-24, 2005

Indexing

ISI Web of Knowledge - 0 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-000-6HK

DOI: 10.1080/08977190903184670

Abstract (EN): Preeclampsia (PE) is a pathological condition of the placenta that affects the mother and can adversely influence the feto-placental unit. Placental growth factor (PIGF) is synthetized in the placenta, playing a role in placental development and function. Our aim was clarify the role of PIGF in PE, by studying and comparing the PlGF levels of maternal blood and umbilical cord blood (UCB) in normal and preeclamptic (PEc) pregnancies. Our data suggest a placental dysfunction in PE, as showed by the significantly decreased levels of PlGF in maternal and UCB. The reduced PIGF in PEc mothers seems to be associated with a disturbance in the uteroplacental unit, as suggested by the significant positive correlation between maternal and fetal PlGF values.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5