Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Alexandra Moura (Author) Other; Jose Madureira (Author) Other; Pablo Alija (Author) Other; Joao Carlos Fernandes (Author) Other; Jose Gerardo Oliveira (Author) Other; Martin Lopez (Author) Other; Madalena Filgueiras (Author) Other; Leonilde Amado (Author) Other; Maria Sameiro Faria (Author) Other; Vasco Miranda (Author) Other; Alice Santos Silva (Author) FFUP; Elisio Costa (Author) FFUP

Journal

Title: Aging And Disease

Vol. 6

Pages: 17-26

ISSN: 2152-5250

Publisher: International Society on Aging and Disease

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 2 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-00A-CFF

DOI: 10.14336/ad.2014.0514

Abstract (EN): This work aimed to evaluate how aging could influence patients' perception of health quality of life (HRQOL), as well as, the effect of aging on dialysis adequacy and in hematological, iron status, inflammatory and nutritional markers. In this transversal study were enrolled 305 ESRD patients under online-hemodiafiltration (OL-HDF) (59.67% males; 64.9 +/- 14.3 years old). Data about comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patient's records. Moreover, HRQOL score, by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF), was assessed. Analyzing the results according to quartiles of age, significant differences were found for some parameters evaluated by the KDQOL-SF instrument, namely for work status, physical functioning and role-physical, which decreased with increasing age. We also found a higher proportion of diabetic patients, a decrease in creatinine, iron, albumin serum levels, transferrin saturation and nPCR, with increasing age. Moreover, significant negative correlations were found between age and mean cell hemoglobin concentration, iron, transferrin saturation, albumin, nPCR, work status, physical functioning and role-physical. In conclusion, our results showed that aging is associated with a decreased work status, physical functioning and role-physical, with a decreased dialysis adequacy, iron availability and nutritional status, and with an increased proportion of diabetic patients and of patients using central venous catheter, as the vascular access. The knowledge of these changes associated with aging, which have impact in the quality of life of the patients, could be useful in their management.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10