Biochemical and metabolic effects of a short-term exposure to nanoparticles of titanium silicate in tadpoles of Pelophylax perezi (Seoane)

• Type: Article in International Scientific Journal
• Date: 2013

Authors

Salvaterra, T (Author) Other; Alves, MG (Author) Other; Domingues, I (Author) Other; Pereira, R (Author) FCUP; Rasteiro, MG (Author) Other; Carvalho, RA (Author) Other; Soares, AMVM (Author) Other; Lopes, I (Author) Other

Journal

Title: Aquatic Toxicology

Vol. 128

Pages: 190-192

ISSN: 0166-445X

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 18 Citations

Scopus - 19 Citations

Scientific classification

FOS: Medical and Health sciences > Basic medicine

Other information

Authenticus ID: P-005-2GM

DOI: 10.1016/j.aquatox.2012.12.014

Abstract (EN): This study aimed to evaluate sublethal effects of a short-term exposure (96 h) to titanium silicate nanoparticles (TiSiO4-NP) on Pelophylax perezi tadpoles. Tadpoles were exposed to five concentrations of TiSiO4-NP (8.2, 10.2, 12.8, 16 and 20 mg/L) plus a control. Effect criteria were: mortality, cholinesterases, glutathione S-transferases, lactate dehydrogenase, and catalase activities, and alanine and lactate contents. Light scattering was used for physical characterization of TiSiO4-NP suspensions, revealing a high aggregation state of the NP, consistent with low z-potential values (<30 mV). Mortality among TiSiO4-NP treatments was <11%. Significant differences relatively to the control were observed at the biochemical level (for CAT and LDH) and in lactate and alanine contents, which may end-up in increased oxidative stress. Overall, some of the monitored endpoints suggest metabolic alterations in TiSiO4-NP exposed tadpoles, highlighting the potential of TiSiO4-NP long-term effects on these organisms.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3