Spanish population data and forensic usefulness of a novel Y-STR set (DYS437, DYS438, DYS439, DYS460, DYS461, GATA a10, GATA c4, GATA h4)

• Type: Article in International Scientific Journal
• Date: 2003

Authors

Zarrabeitia, MT (Author) Other; Riancho, JA (Author) Other; Gusmao, L (Author) Other; Lareu, MV (Author) Other; Sanudo, C (Author) Other; Amorim, A (Author) FCUP; Carracedo, A (Author) Other

Journal

Title: International Journal of Legal Medicine

Vol. 117

Pages: 306-311

ISSN: 0937-9827

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 9 Citations

Scopus - 11 Citations

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-000-EZQ

DOI: 10.1007/s00414-003-0393-4

Abstract (EN): DNA typing of 8 recently described STRs on the Y chromosome was carried out by means of 2 multiplex amplification reactions for 134 unrelated males from Cantabria, a region in northern Spain. Multiplex 1 included loci DYS460 (GATA A7.1), GATA A10, GATA H4 and DYS439; multiplex 2 included DYS461 (GATA A7.2), GATA C4, DYS437 and DYS438. Haplotype diversity was found to be 99.36%, similar to that obtained with the standard 9-STR set ('minimal haplotype') of the European Y-user group (99.35%). The 13-locus haplotype resulting from the combination of the standard minimal haplotype and the 4-locus multiplex 1 showed a 99.89% diversity. Further inclusion of the 4 loci in multiplex 2 resulted in a haplotype diversity of 99.93%. The combination of the 'minimal haplotype' and the multiplex 1 in the present study may be an efficient way of increasing the power of discrimination in forensic cases.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6