Microstructural characterization and in vitro apatite formation in CaO-P2O5-TiO2-MgO-Na2O glass-ceramics

• Type: Article in International Scientific Journal
• Date: 2001

Authors

Zhang, Y (Author) Other; Santos, JD (Author) FEUP

Journal

Title: Journal of the European Ceramic Society

Vol. 21

Pages: 169-175

ISSN: 0955-2219

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 19 Citations

ISI Web of Science

Scopus - 20 Citations

COMPENDEX

Scientific classification

FOS: Engineering and technology > Materials engineering

CORDIS: Technological sciences > Engineering > Biomaterial engineering ; Technological sciences > Engineering > Biomedical enginnering

Other information

Authenticus ID: P-000-WHX

DOI: 10.1016/s0955-2219(00)00202-8

Abstract (EN): Bulk calcium phosphate glass and glass-ceramic with CaO/P2O5 molar ratio = 1.25 were prepared through introducing small amounts of Na2O, MgO, and TiO2 into the glass. Using XRD analysis, biocompatible beta -Ca2P2O7 (beta -DCP) and more soluble Ca and Na-containing phases were clearly identified in the microstructure. In vitro bioactivity was assessed by immersion testing in SBF-simulated body fluid and apatite crystals were formed after 4 and 8 weeks of soaking. Porous microstructure was produced through dissolution of soluble phases and desirable porous structure may be achieved by controlling size and distribution of these phases and the leaching process. Therefore, this glass-ceramic is expected to be used as bone repair and regeneration implants and drug delivery carrier.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7