Meconium aspiration syndrome: risk factors and predictors of severity

• Type: Article in International Scientific Journal
• Date: 2019

Authors

Oliveira, CPL (Author) Other; Filipa Flor-de-Lima (Author) FMUP; Rocha, GMD (Author) Other; Machado, AP (Author) Other; Guimarães H (Author) FMUP

Journal

Title: Journal of Maternal-Fetal and Neonatal Medicine

Vol. 32

Pages: 1492-1498

ISSN: 1476-7058

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 17 Citations

Scopus - 17 Citations

Other information

Authenticus ID: P-00Q-6TA

DOI: 10.1080/14767058.2017.1410700

Abstract (EN): Purpose: To identify risk factors and predictors of severity associated with meconium aspiration syndrome (MAS) in the patients admitted to the neonatal intensive care unit (NICU). Materials and methods: Retrospective study including newborns admitted, between 2005 and 2015, with a diagnosis of MAS. Results: Of the newborns admitted to the NICU, 0.66% were diagnosed with MAS. These had higher prevalence of caesarean delivery (p < .001), nonreassuring or abnormal cardiotocography (CTG) (p < .001), intrapartum maternal fever (p = .002), Apgar scores at the first minute <7 (p < .001) and need of endotracheal intubation at birth (p < .001). Newborns with severe MAS had higher median reactive C protein (86.9 versus 9.65, p = .001) and 73.3% had pulmonary hypertension (p = .027). They required significantly more days of oxygen therapy, mechanical ventilation, nitric oxide, inotropic, and surfactant therapy, as well as longer hospital stay. Conclusions: Nonreassuring or abnormal CTG and low Apgar score at the first minute were established as risk factors for MAS and need of surfactant therapy as a predictor of severity.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7