Eco-friendly LC-MS/MS method for analysis of multi-class micropollutants in tap, fountain, and well water from northern Portugal

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Marta O. Barbosa (Author) FEUP; Ana Rita Ribeiro (Author) FEUP; Manuel F. R. Pereira (Author) FEUP; Adrián M. T. Silva (Author) FEUP

Journal

Title: Analytical and Bioanalytical Chemistry

Vol. 408

Pages: 8355-8367

ISSN: 1618-2642

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 11 Citations

Scopus - 24 Citations

Associated Projects

AIProcMat@N2020 - Advanced Industrial Processes and Materials for a Sustainable North Region of Portugal2020

LSRE-LCM - Laboratório de Processos de Separação e Reação - Laboratório de Catálise e Materiais

NEPCAT - Novo equipamento envolvendo processos catalíticos integrados para tratamento de poluentes orgânicos e desinfeção de águas

Other information

Authenticus ID: P-00M-52E

DOI: 10.1007/s00216-016-9952-7

Abstract (EN): Organic micropollutants present in drinking water (DW) may cause adverse effects for public health, and so reliable analytical methods are required to detect these pollutants at trace levels in DW. This work describes the first green analytical methodology for multi-class determination of 21 pollutants in DW: seven pesticides, an industrial compound, 12 pharmaceuticals, and a metabolite (some included in Directive 2013/39/EU or Decision 2015/495/EU). A solid-phase extraction procedure followed by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (offline SPE-UHPLC-MS/MS) method was optimized using eco-friendly solvents, achieving detection limits below 0.20 ng L-1. The validated analytical method was successfully applied to DW samples from different sources (tap, fountain, and well waters) from different locations in the north of Portugal, as well as before and after bench-scale UV and ozonation experiments in spiked tap water samples. Thirteen compounds were detected, many of them not regulated yet, in the following order of frequency: diclofenac > norfluoxetine > atrazine > simazine > warfarin > metoprolol > alachlor > chlorfenvinphos > trimethoprim > clarithromycin ae carbamazepine ae PFOS > citalopram. Hazard quotients were also estimated for the quantified substances and suggested no adverse effects to humans.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13