Congenital posthemorrhagic hydrocephalus: A case of fetomaternal alloimmune thrombocytopenia

• Tipo: Artigo em Revista Científica Internacional
• Data: 2007

Autores

Povoa, AM (Autor) Outra; ramalho, c (Autor) Outra; Machado, AP (Autor) Outra; matias, a (Autor) FMUP; Montenegro N (Autor) FMUP

Revista

Título: Fetal Diagnosis and Therapy

Vol. 22

Páginas: 321-324

ISSN: 1015-3837

Editora: Karger

Indexação

ISI Web of Knowledge - 6 Citações

Scopus - 6 Citações

Outras Informações

ID Authenticus: P-004-D57

DOI: 10.1159/000103288

Abstract (EN): Fetal/neonatal alloimmune thrombocytopenia (NAIT) results from fetomaternal mismatch for human platelet alloantigens leading to antibody-mediated destruction of fetal platelets. This is one of the most common causes of severe thrombocytopenia in the newborn with an incidence of 1/800-1,000. In the most severe cases, NAIT may result in intracranial hemorrhage and may lead to death or neurologic sequelae. We report a case of fetal hydrocephalus caused by NAIT and discuss the importance of making an accurate prenatal diagnosis to improve the management of the current pregnancy and the outcome of subsequent pregnancies. Screening of female siblings of affected cases is recommended in order to detect at-risk individuals. Copyright (c) 2007 S. Karger AG, Basel.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4