Blood Flow Visualization and Measurements in Microfluidic Devices Fabricated by a Micromilling Technique

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Jaron Singhal (Autor) Outra; Diana Pinho (Autor) Outra; Raquel Lopes (Autor) Outra; Patricia C. Sousa (Autor) FEUP; Valdemar Garcia (Autor) Outra; Helmut Schütte (Autor) Outra; Rui Lima (Autor) FEUP; Stefan Gassmann (Autor) Outra

Revista

Título: Micro and Nanosystems

Vol. 7 Nº 3

Páginas: 148-153

ISSN: 1876-4029

Editora: Bentham Science

Indexação

Scopus

Outras Informações

DOI: 10.2174/1876402908666160106000332

Abstract (EN): The most common and used technique to produce microfluidic devices for biomedical applications is the soft-lithography. However, this is a high cost and time-consuming technique. Recently, manufacturers were able to produce milling tools smaller than 100 m and consequently have promoted the ability of the micromilling machines to fabricate microfluidic devices capable of performing cell separation. In this work, we show the ability of a micromilling machine to manufacture microchannels down to 30 m and also the ability of a microfluidic device to perform partial separation of red blood cells from plasma. Flow visualization and measurements were performed by using a high-speed video microscopy system. Advantages and limitations of the micromilling fabrication process are also presented.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6