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Abstract | Fluoroorganic compounds are a class of chemicals that are thriving in virtually all economic sectors, essentially due to the unique properties of the fluorine atom. Their environmental presence is mainly a result of anthropogenic action, with the pharmaceutical and agrochemical industries representing two important sectors in this regard. Due to the fact that the majority of these compounds are emergent xenobiotic pollutants, a lot is yet to be known regarding their biodegradability and hazardous nature. Thus, the study of biodegradation of fluoroorganics and the development of suitable bioremediation technologies capable of mitigating their environmental impact is urgently needed.