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FC6 - Departamento de Ciência de Computadores FC5 - Edifício Central FC4 - Departamento de Biologia FC3 - Departamento de Física e Astronomia e Departamento GAOT FC2 - Departamento de Química e Bioquímica FC1 - Departamento de Matemática

Courses

Master's degree in Cell and Molecular Biology

General information

Official Code: 6022
Acronym: M:BCM

Certificates

  • Master's degree in Cell and Molecular Biology (120 ECTS credits)
  • Specialization in Celular and Molecular Biology (60 ECTS credits)

Courses Units

Cell Cultures

B4014 - ECTS

To enable students to be familiar with concepts of in vitro cell (animal and plant cells) cultures and their practical applications.

Molecular Diagnostics

B4016 - ECTS

To understand basic principles behind molecular diagnostics To recognise different contexts of applications To master main techniques and analytical tools

Molecular Cell Physiology

B4026 - ECTS

The Cell is the fundamental unit of life and the knowledge of its physiology forms the foundation upon which all Biology is built, as well as its applications, including modern Medicine. The objective of this UC is to address some key cellular processes at the level of the state of the art and of the ongoing construction of new knowledge, transmitting the great molecular complexity of cell physiology, and the advances of the experimental approaches used in its study.

Forensic Genetics

B4051 - ECTS

To understand the use of genetics in forensics.
To master the communication of information between the court and the experts.
To understand and evaluate the ethical and professional deontology in forensic expertise.

Microbiology Laboratory

B4029 - ECTS

Bibliography search and organization of a database.

Discussion of scientific papers.

Improve knowledge on microbiological techniques used commonly in nowadays research.

Develop capacities to conceive structure and put in place an experimental work/design.

Organization of results obtained in the experimental work, elaboration of a poster as for presentation in a scientific meeting.

Elaboration of a manuscript.

DNA Manipulation and Synthetic Biology

B4030 - ECTS

Aims of the course unit include: To provide advanced concepts about DNA manipulation, recombinant DNA technologies, cloning and their applications in genetic transformation of organisms and PCR focusing on the molecular techniques involved in the production of recombinant proteins. Provide training in the use of basic bioinformatics tools in analysis and planning of a protein expression project. Primer design and gene optimization. Provide laboratory “hands-on” training in cloning of gene(s) into expression vectors containing different tags and fusion proteins and transformation into appropriate bacterial strains. Familiarization with analysis of original scientific articles, logic of experimental design and data analysis. Training in project work, experimental design and in oral and written communication. Provide the basic concepts and terminology related to synthetic biology.

 

Molecular Markers: Recombining Genomic Regions

B4035 - ECTS

To consolidate the knowledge that sustains the use of recombining genetic markers in the forensic context.

Bio-imaging

B4045 - ECTS

This course mainly techniques-based is designed: to provide a thorough understanding of modern microscopy technique; to present strategies in basic molecular biology technologies that enable the study of living cells with fluorescent proteins; and to provide essential knowledge how to use antibody technology to localise proteins.

Genome, Transcriptome, and Proteome in Silico Analysis

B4002 - ECTS

Introduction and training in bioinformatics tools focusing on the user's standpoint. Case-studies in the context of ongoing research projects.

Plant Molecular Biology

B4009 - ECTS

This UC addresses the molecular, genomic, biochemical, cell biological, and computational approaches to understand plant physiology and development at a molecular level. The biotechnological applications powered by molecular tools are also addressed. 

Biotecnology of Assisted Reproduction

B4011 - ECTS

To provide theoretical and practical basis of human assisted reproduction to enable the student to start supervised laboratorial work.

Molecular Evolution

B4024 - ECTS

The students should understand key concepts in molecular evolution and integrate this knowledge towards the development of working hypothesis to explain specific scientific questions. In addition the students should acquire the know-how to choose the most adequate methodologies to validate or refuse the different evolutionary hypotheses.

Molecular Markers: Mitochondrial DNA

B4033 - ECTS

Consolidate the knowledge that sustains the use of mitochondrial DNA in the forensic context

Molecular Microbiology

B4036 - ECTS

The objectives of Molecular Microbiology, must translate the specific skills that are expected to be developed by the students, namely: • Plan, execute and interpret experiments. • Familiarization with routine techniques in microbiology and biology molecular (culture of microorganisms, PCR, cloning, gel electrophoresis of agarose and polyacrylamide, Western blot, sequencing etc.). • Familiarization with databases of genomic information and protein and bioinformatics tools (Blast, ClustalW, Primer3, etc.). • Autonomy in search of scientific literature on a particular topic and using the free tools such as PubMed of NCBI also available in the Virtual Library of UP, in particular the Web of Knowledge. • Develop the capacity of oral and written communication. • Develop the capacity of synthesis and critical thinking.

Reproduction in Arabidopsis: a Molecular Approach

BIOL4052 - ECTS

 

The main objectives of this course are to provide students with ability to handle all bio-informatics tools available to the plant that is considered a model in molecular biology.
Familiarize themselves with advanced processing plants, handling of single and double null mutants and mutants with genes labeled with different tags. Employ techniques of emasculation and pollination of plants, studies semi in vivo of the pollen tube growth and visualization of molecular markers by fluorescence microscopy and electronic microscopy. Evaluation of results of Real Time-PCR and evaluating the results of microarrays.

Oxidative Stress and Antioxidant Defenses

B4043 - ECTS

- To enable students to identify the factors affecting the stress response and the production pathways of the reactive oxygen species.
- To describe the enzymatic and non-enzymatic antioxidant defense systems and explain their physiological function.
- To provide students with knowledge of the physiological and biochemical processes underlying the damage caused by abiotic stresses and the mechanisms of adaptation and acclimation of plants and animals to stressful situations.
- To identify strategies to increase the tolerance of plants and animals to certain types of stress.
-Planning an ecotoxicological test to assess oxidative stress

Dissertation

B5010 - ECTS For completion the master's degree a dissertation is required in a field of MCB. the main objective is that the student should master a subject of the dissertation, from a scientific and technical point of view, and its framework within the current research in the area. The student should also be able to communicate / disseminate the selected scientific  topic from a written and oral point of view, and also in terms of peer discussion

Internship

B5003 - ECTS For completion the master's degree a Dissertation or an Internship Report is required.

Project of Dissertation

B5001 - ECTS

The curricular unit "Project of Dissertation" is one of the ways for demonstrating that the Master subjects have been learned. The student should write a research proposal on a Cell and Molecular Biology topic. The written proposal should include a short review of the literature, a description of the goals, hypotheses to be tested, procedures to be used and a projected analysis of results leading to the Dissertation, according to the rules given.

Internship Project

B5000 - ECTS

The curricular unit "Project of internship" is one of the ways for demonstrating that the Master subjects have been learned in an internship environment. The student should write a research proposal on a Cell and Molecular Biology topic. The written proposal should include a short review of the literature, a description of the goals, hypotheses to be tested, procedures to be used and a projected analysis of results leading to the Internship Dissertation, according to the rules given.

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