Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

• Tipo: Artigo em Revista Científica Internacional
• Data: 2005

Autores

Granja, PL (Autor) Outra; De Jeso, B (Autor) Outra; Bareille, R (Autor) Outra; Rouais, F (Autor) Outra; Baquey, C (Autor) Outra; Barbosa, MA (Autor) FEUP

Revista

Título: European Cells and Materials

Vol. 10

Páginas: 31-39

ISSN: 1473-2262

Editora: AO Research Institute Davos

Indexação

ISI Web of Knowledge

Scopus - 15 Citações

Outras Informações

ID Authenticus: P-007-EEA

Abstract (EN): The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colonized the surface of the materials. Moreover, since the early days in culture, between the surface of the materials and attached cells a continuous granulated hydroxyapatite layer was formed. It has been previously demonstrated in vitro, but without cells, that these materials did not mineralize. Hence, it seems that HBMSC promoted the mineralization of the surface.

Idioma: Inglês

Tipo (Avaliação Docente): Científica