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International Journals
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2021

Trichilia catigua and Turnera diffusa extracts: In vitro inhibition of tyrosinase, antiglycation activity and effects on enzymes and pathways engaged in the neuroinflammatory process.
Bernardo, J., Malheiro, I., Videira, R.A., Valentão, P., Santos, A.C., Veiga, F., Andrade, P.B.
Journal of Ethnopharmacology, 271, art. no. 113865, 2021.
Valorisation of kitul, an overlooked food plant: Phenolic profiling of fruits and inflorescences and assessment of their effects on diabetes-related targets.
Ferreres, F., Andrade, C., Gomes, N.G.M., Andrade, P.B., Gil-Izquierdo, A., Pereira, D.M., Suksungworn, R., Duangsrisai, S., Videira, R.A., Valentão, P.
Food Chemistry, 342, art. no. 128323, 2021.
Cassia sieberiana DC. leaves modulate LPS-induced inflammatory response in THP-1 cells and inhibit eicosanoid-metabolizing enzymes.
Macedo, T., Ferreres, F., Pereira, D.M., Oliveira, A.P., Gomes, N.G.M., Gil-Izquierdo, Á., Valentão, P., Araújo, L., Andrade, P.B.
Journal of Ethnopharmacology, 269, art. no. 113746, 2021.
Activation of caspase-3 in gastric adenocarcinoma AGS cells by Xylopia aethiopica (Dunal) A. Rich. fruit and characterization of its phenolic fingerprint by HPLC-DAD-ESI(Ion Trap)-MSn and UPLC-ESI-QTOF-MS².
Ribeiro, V., Ferreres, F., Macedo, T., Gil-Izquierdo, Á., Oliveira, A.P., Gomes, N.G.M., Araújo, L., Pereira, D.M., Andrade, P.B., Valentão, P.
Food Research International, 141, art. no. 110121, 2021.
Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum.
Pech-Puch, D., Joseph-Nathan, P., Burgueño-Tapia, E., González-Salas, C., Martínez-Matamoros, D., Pereira, D.M., Pereira, R.B., Jiménez, C., Rodríguez, J. Scientific Reports, 11 (1), art. no. 496, 2021.
Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery.
Veloso, S.R.S., Jervis, P.J., Silva, J.F.G., Hilliou, L., Moura, C., Pereira, D.M., Coutinho, P.J.G., Martins, J.A., Castanheira, E.M.S., Ferreira, P.M.T.
Materials Science and Engineering C, 122, art. no. 111869, 2021.

2020

Polyphenols from Brown Seaweeds (Ochrophyta, Phaeophyceae): Phlorotannins in the Pursuit of Natural Alternatives to Tackle Neurodegeneration.
Barbosa, M., Valentão, P., Andrade, P.B.
Marine drugs, 18 (12), 654, 2020.
In vitro multifunctionality of phlorotannin extracts from edible Fucus species on targets underpinning neurodegeneration.
Barbosa, M., Valentão, P., Ferreres, F., Gil-Izquierdo, Á., Andrade, P.B.
Food Chemistry, 333, art. no. 127456, 2020.
Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicals.
Andrade, C., Gomes, N.G.M., Duangsrisai, S., Andrade, P.B., Pereira, D.M., Valentão, P.
Journal of Ethnopharmacology, 263, art. no. 113177, 2020.
Jasonia glutinosa (L.) DC., a traditional herbal medicine, reduces inflammation, oxidative stress and protects the intestinal barrier in a murine model of colitis.
Valero, M.S., González, M., Ramón-Gimenez, M., Andrade, P.B., Moreo, E., Les, F., Fernandes, F., Gómez-Rincón, C., Berzosa, C., García de Jalón, J.A., Arruebo, M.ª.P., Plaza, M.Á., Köhler, R., López, V., Valentão, P., Castro, M.
Inflammopharmacology, 28 (6), pp. 1717-1734, 2020.
Adding value to polyvinylpolypyrrolidone winery residue: A resource of polyphenols with neuroprotective effects and ability to modulate type 2 diabetes-relevant enzymes.
Rocha, L., Neves, D., Valentão, P., Andrade, P.B., Videira, R.A.
Food Chemistry, 329, art. no. 127168, 2020.
Gustavia gracillima Miers. flowers effects on enzymatic targets underlying metabolic disorders and characterization of its polyphenolic content by HPLC-DAD-ESI/MSⁿ.
Andrade, C., Ferreres, F., Gomes, N.G.M., Gil-Izquierdo, A., Bapia, S., Duangsrisai, S., Pereira, D.M., Andrade, P.B., Valentão, P.
Food Research International, 137, art. no. 109694, 2020.
Erratum: Isolation of cells specialized in anticancer alkaloid metabolism by fluorescence-activated cell sorting (Plant Physiology (2016) 171 (2371-2378).
Carqueijeiro, I., Guimãraes, A.L., Bettencourt, S., Martinez-Cortés, T., Guedes, J.G., Gardner, R., Lopes, T., Andrade, C., Bispo, C., Martins, N.P., Andrade, P., Valentão, P., Valente, I.M., Rodrigues, J.A., Duarte, P., Sottomayor, M.
Plant Physiology, 184 (3), p. 1613, 2020.
Echium plantagineum L. honey: Search of pyrrolizidine alkaloids and polyphenols, anti-inflammatory potential and cytotoxicity.
Moreira, R., Fernandes, F., Valentão, P., Pereira, D.M., Andrade, P.B.
Food Chemistry, 328, art. no. 127169, 2020.
Isolation of astaxanthin monoesters from the microalgae Haematococcus pluvialis by high performance countercurrent chromatography (HPCCC) combined with high performance liquid chromatography (HPLC).
Fábryová, T., Tůmová, L., da Silva, D.C., Pereira, D.M., Andrade, P.B., Valentão, P., Hrouzek, P., Kopecký, J., Cheel, J.
Algal Research, 49, art. no. 101947, 2020.
Plitidepsin to treat multiple myeloma.
Gomes, N.G.M., Valentaõ, P., Andrade, P.B., Pereira, R.B.
Drugs of Today, 56 (5), pp. 337-347, 2020.
Inhibition of proinflammatory enzymes and attenuation of IL-6 in LPS-challenged RAW 264.7 macrophages substantiates the ethnomedicinal use of the herbal drug Homalium bhamoense cubitt & W.W.Sm.
Suksungworn, R., Andrade, P.B., Oliveira, A.P., Valentão, P., Duangsrisai, S., Gomes, N.G.M.
International Journal of Molecular Sciences, 21 (7), art. no. 2421, 2020.
Centaurium Erythraea Extracts Exert Vascular Effects through Endothelium- And Fibroblast-dependent Pathways.
Chda, A., El Kabbaoui, M., Fresco, P., Silva, D., Gonçalves, J., Oliveira, A.P., Andrade, P.B., Valentão, P., Tazi, A., El Abida, K., Bencheikh, R.
Planta Medica, 86 (2), pp. 121-131, 2020.
Cytotoxic Plant Extracts towards Insect Cells: Bioactivity and Nanoencapsulation Studies for Application as Biopesticides.
Lopes, A.I.F., Monteiro, M., Araújo, A.R.L., Rodrigues, A.R.O., Castanheira, E.M.S., Pereira, D.M., Olim, P., Fortes, A.G., Gonçalves, M.S.T.
Molecules (Basel, Switzerland), 25 (24), 2020.
New eugenol derivatives with enhanced insecticidal activity.
Fernandes, M.J.G., Pereira, R.B., Pereira, D.M., Fortes, A.G., Castanheira, E.M.S., Gonçalves, M.S.T.
International Journal of Molecular Sciences, 21 (23), art. no. 9257, pp. 1-14, 2020.
Natural pigments of anthocyanin and betalain for coloring soy-based yogurt alternative.
Dias, S., Castanheira, E.M.S., Gil Fortes, A., Pereira, D.M., Sameiro T. Gonçalves, M.
Foods, 9 (6), art. no. 771, 2020.
Application of natural pigments in ordinary cooked ham.
Dias, S., Castanheira, E.M.S., Fortes, A.G., Pereira, D.M., Rodrigues, A.R.O., Pereira, R., Gonçalves, M.S.T.
Molecules, 25 (9), art. no. 2241, 2020.
Endoplasmic reticulum stress signaling in cancer and neurodegenerative disorders: Tools and strategies to understand its complexity.
da Silva, D.C.; Valentão, P.; Andrade, P.B.; Pereira, D.M.
Pharmacological Research, 155, 104702, 2020
Evaluating the in vitro potential of natural extracts to protect lipids from oxidative damage.
Félix, R.; Valentão, P.; Andrade, P.B.,; Félix, C.; Novais, S.C.; Lemos, M.F.L.
Antioxidants, 9 (3), 231, 2020.
New chalcone-type compounds and 2-pyrazoline derivatives: synthesis and caspase-dependent anticancer activity.
Chouiter, M.I.; Boulebd, H.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Belfaitah, A.; Silva, A.M.
Future Medicinal Chemistry, 12 (6), 493-509, 2020.
Anti-inflammatory properties of Xylopia aethiopica leaves: Interference with pro-inflammatory cytokines in THP-1-derived mcrophages and flavonoid profiling.
Macedo, T.; Ribeiro, V.; Oliveira, A.P.; Pereira, D.M.; Fernandes, F.; Gomes, N.G.M.; Araújo, L.; Valentão, P.; Andrade, P.B.
Journal of Ethnopharmacology, 248, 112312 (2020).
Biological evaluation of naproxen–dehydrodipeptide conjugates with self-hydrogelation capacity as dual LOX/COX inhibitors.
Moreira, R., Jervis, P.J., Carvalho, A., Ferreira, P.M.T., Martins, J.A., Valentão, P., Andrade, P.B., Pereira, D.M.
Pharmaceutics, 12 (2), 122, 2020.
Fatty acid patterns of the kelps Saccharina latissima, Saccorhiza polyschides and Laminaria ochroleuca: Influence of changing environmental conditions.
Barbosa, M.; Fernandes, F.; Pereira, D.M.; Azevedo, I.C.; Sousa-Pinto, I.; Andrade, P.B.; Valentão, P.
Arabian Journal of Chemistry, 13 (1), 45-58, 2020.
Enhancement of the anti-inflammatory properties of grape pomace treated by: Trametes versicolor.
Bucić-Kojić, A.; Fernandes, F.; Silva, T.; Planinić, M.; Tišma, M.; Šelo, G.; Šibalić, D.; Pereira, D.M.; Andrade, P.B.
Food and Function, 11 (1), 680-688, 2020.

2019

Exploring Montagu's crab: Primary and secondary metabolites and enzyme inhibition.
Oliveira, A.P.; Lopes, A.C.; Silva, M.; Andrade, P.B.; Valentão, P.
Arabian Journal of Chemistry, 12 (8), 4017-4025, 2019.
Global, regional, and national burden of brain and other CNS cancer, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.
Patel, A.P.; (…); Pereira, D.M., (…); Fitzmaurice, C.
The Lancet Neurology, 18 (4), 376-393, 2019.
Dehydropeptide-based plasmonic magnetogels: A supramolecular composite nanosystem for multimodal cancer therapy.
Veloso, S. R. S.; Martins, J. A.; Hilliou, L.; Amorim, C. O.; Amaral, V. S.;. Almeida, B. G; Jervis, P. J.; Moreira, R.; Pereira, D. M.; Coutinho, P. J. G.; Ferreira, P. M. T.; Castanheira, E. M. S.
Journal of Materials Chemistry B, 8 (1), 45-64, 2019.
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.
Nichols, E.; (…); Pereira, D.M., (…); Murray, C.J.L.
The Lancet Neurology, 18 (1), 88-106, 2019.
Phenolic profiling and biological potential of Ficus curtipes Corner leaves and stem bark: 5-lipoxygenase inhibition and interference with NO levels in LPS-stimulated RAW 264.7 macrophages.
Andrade, C.; Ferreres, F.; Gomes, N.G.M.; Duangsrisai, S.; Srisombat, N.; Vajrodaya, S.; Pereira, D.M.; Gil-Izquierdo, A.; Andrade, P.B.; Valentão, P.
Biomolecules, 9, 400, 2019
Double the chemistry, double the fun: Structural diversity and bioactivity of marine-derived diketopiperazine dimers
Gomes, N.G.M.; Andrade, P.B.; Valentão, P.
Mar Drugs, 17, 551, 2019
Extraction of phospholipid-rich fractions from egg yolk and development of liposomes entrapping a dietary polyphenol with neuroactive potential.
Bernardo, J.; Videira, R.A.; Valentão, P.; Veiga, F.; Andrade, P.B.
Food Chem Toxicol 133, 110749, 2019
Jasonia glutinosa (L.) DC., a traditional herbal medicine, reduces inflammation, oxidative stress and protects the intestinal barrier in a murine model of colitis.
Valero, M.S.; González, M.; Gimenez, M.R.; Andrade, P.B.; Moreo, E.; Les, F.; Fernandes, F.; Gómez-Rincón, C.; Berzosa, C.; García de Jalón, J.A.; Arruebo, M.P.; Plaza, M.A.; Köhler, R.; López, V.; Valentão, P.; Castro, M.
Inflammopharmacology 2019
Flavonoid composition of Salacia senegalensis (Lam.) DC leaves, evaluation of antidermatophytic effects, and potential amelioration of the associated inflammatory response.
Gomes, N.G.M.; Oliveira, A.P., Cunha, D.; Pereira, D.M.; Valentão, P.; Pinto, E.; Araújo, L.; Andrade, P.B.
Molecules 24, 2530, 2019
Benzoquinones from Cyperus spp. trigger IRE1α-independent and PERK-dependent ER stress in human stomach cancer cells and are novel proteasome inhibitors.
Ribeiro, V.; Andrade, P.B.; Valentão, P.; Pereira, D.M.
Phytomedicine 63, 153017, 2019
Marine-derived anti-cancer agents: Clinical benefits, innovative mechanisms and new targets.
Pereira, R.B.; Evdokimov, N.M.; Lefranc, F.; Valentão, P.; Kornienko, A.; Pereira, D.M.; Andrade, P.B.; Gomes, N.G.M.
Mar. Drugs 17, 329, 2019
Anti-inflammatory effects of 5α,8α-epidioxycholest-6-en-3β-ol, a steroidal endoperoxide isolated from Aplysia depilans based on bioguided fractionation and NMR analysis.
Pereira, R.B.; Pereira, D.M.; Jiménez, C.; Rodríguez, J., Nieto, R.M.; Videira, R.A.; Silva, O.; Andrade, P.B.; Valentão, P.
Mar Drugs 17, 330, 2019
Influence of shading treatment on yield, morphological traits and phenolic profile of sweet basil (Ocimum basilicum L.) .
Castronuovo, D.; Russo, D.; Libonati, R.; Faraone, I.; Candido, V.; Picuno, P.; Andrade, P.; Valentão, P.; Milella. L. Mar.
Sci Hortic 254, 91-98, 2019
Novel styrylpyrazole-glucosides and their dioxolo-bridged doppelgangers: synthesis and cytotoxicity.
Carreira, A.R.F.; Pereira, D.M.; Andrade, P.B.; Valentão, P.; Silva, A.M.S.; Braga, S.S.; Silva, V.L.M.
New J Chem 43, 8299-8310, 2019
Health Effects of Dietary Risks in 195 Countries, 1990-2017: A systematic analysis for the Global Burden of Diseases Study 2017.
Afshin, A, (…), Pereira, D.M., (…), Murray, C.J.L.
The Lancet, 2019, 393, 1958-1972, 2019
Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995-2050.
Chang,A., (…), Pereira, D.M., (…), Dieleman, J.L.
The Lancet, 393, 2233-2260, 2019
Comparison of different green-extraction techniques and determination of the phytochemical profile and antioxidant activity of Echinacea angustifolia L. extracts.
Russo, D.; Faraone, I.; Labanca, F.; Sinisgalli, C.; Bartolo, M.; Andrade, P.B.; Valentão, P.; Milella. L.
Phytochem Anal, 1-9, 2019
Phlorotannins from Fucales: Potential to control hyperglycaemia and diabetes-related vascular complications.
Lopes, G. Barbosa, M.; Andrade, P.B.; Valentão, P.
J Appl Phycol, 2019
Magnetic dehydrodipeptide-based self-assembled hydrogels for theragnostic applications.
Carvalho, A.; Gallo, J.; Valentão, P.; Andrade, P.B.; Pereira, D.M.; Hilliou, L.; Ferreira, P.M.T.; Bañobre-López, M.; Martins, J.A.
Nanomaterials 9, 541, 2019
A new insight on elderberry anthocyanins bioactivity: modulation of mitochondrial redox chain functionality and cell redox state.
Neves, D.; Valentão, P.; Bernardo, J.; Oliveira, M.C.; Ferreira, J.M.G.; Pereira, D.M.; Andrade, P.B.; Videira, R.A.
J Funct Foods 56, 145-155, 2019
Bioprospecting of brown seaweeds for biotechnological applications: Phlorotannin actions in inflammation and allergy network.
Barbosa, M.; Lopes, G.; Andrade, P.B.; Valentão, P.
Trends Food Sci Technol 86, 153-171, 2019
Hydrophilic carbon nanomaterial: Characterization by physical-chemical and biologic assays.
Veloso, A.D.; Ferraria, A.M.; Botelho de Rego, A.M.; Tavares, P.B.; Valentão, P.; Pereira, D.M.; Andrade, P.B.; Fernandes, A.J.; Oliveira, M.C.; Videira, R.A.
ChemMedChem 14, 1-14, 2019
Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion.
Popov, C.S.F.C.; Magalhães, B.S.; Goodfellow, B.J.; Bocca, A.L.; Pereira, D.M.; Andrade, P.B.; Valentão, P.; Pereira, P.J.B.; Rodrigues, J.E.; Holanda Veloso Júnior, P.H.; Rezemde, T.M.B.
Peptides 113, 11-21, 2019
HPLC-DAD-ESI/MSn phenolic profile and in vitro biological potential of Centaurium erythraea Rafn aqueous extract.
Kachmar, M.R.; Oliveira, A.P.; Valentão, P.; Gil-Izquierdo, A.; Domínguez-Perles, R.; Ouahbi, A.; El Badaoui, K.; Andrade, P.B.; Ferreres, F.
Food Chem 278, 424-433, 2019
Effect of in vitro gastrointestinal digestion on the total phenolic contents and antioxidant activity of wild Mediterranean edible plant extracts.
Gonçalves, S.; Moreira, E.; Andrade, P.B.; Valentão, P.; Romano, A.
Eur. Food Res. Technol. 245, 753-762, 2019

2018

Edible seaweeds' phlorotannins in allergy: A natural multi-target approach.
Barbosa, M.; Lopes, G.; Valentão, P.; Ferreres, F.; Gil-Izquierdo, A.; Pereira, D.M.; Andrade, P.B.
Food Chem, 265, 233-241, 2018
In vitro multimodal-effect of Trichilia catigua A. Juss. (Meliaceae) bark aqueous extract in CNS targets.
Bernardo, J.; Ferreres, F.; Gil-Izquierdo, A.; Videira, R.A.; Valentão, P.; Veiga, F.; Andrade, P.B.
J Ethnopharmacol, 211, 247-255, 2018
Chemical profiling of edible seaweed (Ochrophyta) extracts and assessment of their in vitro effects on cell-free enzyme systems and on the viability of glutamate-injured SH-SY5Y cells.
Fernandes, F.; Barbosa, M.; Pereira, D.M.; Sousa-Pinto, I.; Valentão, P.; Azevedo, I.C.; Andrade, P.B.
Food Chem Toxicol, 116, 196-206, 2018
Leaves and stem bark from Allophylus africanus P. Beauv.: An approach to anti-inflammatory properties and characterization of their flavonoid profile.
Ferreres, F.; Gomes, N.G.M.; Valentão, P.; Pereira, D.M.; Gil-Izquierdo, A.; Araújo, L.; Silva, T.C.; Andrade, P.B
Food Chem Toxicol,118, 430-438, 2018
Evaluation of the neuroprotective and antidiabetic potential of phenol-rich extracts from virgin olive oils by in vitro assays.
Figueiredo-González, M.; Reboredo-Rodríguez, P.; González-Barreiro, C.; Simal-Gándara, J.; Valentão, P.; Carrasco-Pancorbo, A.; Andrade, P.B.; Cancho-Grande, B.
Food Res Int, 106, 558-567, 2018
Profiling of Heterobranchia sea slugs from Portuguese Coastal waters as producers of anti-cancer and anti-inflammatory agents.
Gomes, N.G.M.; Fernandes, F.; Madureira-Carvalho, Á.; Valentão, P.; Lobo-da-Cunha, A.; Calado, G.; Andrade, P.B.
Molecules, 23, 1027, 2018
Hybrid MS/NMR methods on the prioritization of natural products: Applications in drug discovery.
Gomes, N.G.M.; Pereira, D.M.; Valentão, P.; Andrade, P.B.
J Pharm Biomed Anal, 147, 234-249, 2018
Bioactive properties of Chamaerops humilis L.: antioxidant and enzyme inhibiting activities of extracts from leaves, seeds, pulp and peel.
Gonçalves, S.; Medronho, J.; Moreira, E.; Grosso, C.; Andrade, P.B.; Valentão, P.; Romano, A.
3 Biotech, 8, 88, 2018
Profiling phlorotannins from Fucus spp. of the Northern Portuguese coastline: Chemical approach by HPLC-DAD-ESI/MSn and UPLC-ESI-QTOF/MS.
Lopes, G.; Barbosa, M.; Vallejo, F.; Gil-Izquierdo, Á.; Andrade, P.B.; Valentão, P.; Pereira, D.M.; Ferreres, F.
Algal Res, 29, 113-120, 2018
Beneficial effects of white wine polyphenols-enriched diet on Alzheimer's disease-like pathology.
Mendes, D.; Oliveira, M.M.; Moreira, P.I.; Coutinho, J.; Nunes, F.M.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Videira, R.A.
J. Nutr. Biochem, 55, 165-177, 2018
Pyrrolizidine alkaloids: Chemistry, pharmacology, toxicology and food safety.
Moreira, R.; Pereira, D.; Valentão, P.; Andrade, P.B.
Int J Mol Sci, 19, 1668, 2018
Valorisation of Mangifera indica crop biomass residues.
Mouho, D.G.; Oliveira, A.P.; Kodjo, C.G.; Valentão, P.; Ouattara, Z.A.; Bekro, Y.-A.; Andrade, P.B.
Ind Crop Prod, 124, 284-293, 2018
Chemical findings and in vitro biological studies to uphold the use of Ficus exasperata Vahl leaf and stem bark.
Mouho, D.G.; Oliveira, A.P.; Kodjo, C.G.; Valentão, P.; Gil-Izquierdo, A.; Andrade, P.B.; Ouattara, Z.A.; Bekro, Y.-A.; Ferreres, F.
Food Chem Toxicol, 112, 134-144, 2018
Tuning protein folding in lysosomal storage diseases: The chemistry behind pharmacological chaperones.
Pereira, D.M.; Valentão, P.; Andrade, P.B.
Chem Sci, 9, 1740-1752, 2018
Trace elements in wild edible Aplysia species: Relationship with the desaturation–elongation indexes of fatty acids.
Pereira, R.B.; Almeida, A.A.; Pereira, D.M.; Silva, O.; Andrade, P.B.; Pinto, E.; Valentão, P.
Chemosphere, 208, 682-690, 2018
The consistency between phytotoxic effects and the dynamics of allelochemicals release from Eucalyptus globulus leaves used as bioherbicide Green Manure.
Puig, C.G.; Gonçalves, R.F.; Valentão, P.; Andrade, P.B.; Reigosa, M.J.; Pedrol, N.
J Chem Ecol, 44, 658-670, 2018
Unravelling the bioherbicide potential of Eucalyptus globulus Labill: Biochemistry and effects of its aqueous extract.
Puig, C.G.; Reigosa, M.J.; Valentão, P.; Andrade, P.B.; Pedrol, N.
Plos One, 13, e0192872, 2018
A comparative study on phytochemical profiles and biological activities of Sclerocarya birrea (A.Rich.) Hochst leaf and bark extracts.
Russo, D.; Miglionico, R.; Carmosino, M.; Bisaccia, F.; Andrade, P.B.; Valentão, P.; Milella, L.; Armentano, M.F.
Int J Mol Sci, 19, 186, 2018
Toxicity and structure-activity relationship (SAR) of α,β-dehydroamino acids against human cancer cell lines.
Videira, R.A.; Andrade, P.B.; Monteiro, L.S.; Valentão, P.; Ferreira, P.M.T.; Pereira, D.M.
Toxicol in Vitro, 47, 26-37, 2018
An egg yolk’s phospholipid-pennyroyal nootropic nanoformulation modulates monoamino oxidase-A (MAO-A) activity in SH-SY5Y neuronal model.
Vilamarim, R.; Bernardo, J.; Videira, R.A.; Valentão, P.; Veiga, F.; Andrade, P.B.
J Funct Foods, 46, 335-344, 2018

2017

Recent patents on proteasome inhibitors of natural origin.
Correia, D.; Andrade, P.B.; Ribeiro, V.; Valentão, P.; Pereira, D.M.
Recent Pat Anti-canc, 12, 4-15. 2017
European marketable grain legume seeds: Further insight into phenolic compounds profiles.
Magalhães, S.C.Q.; Taveira, M.; Cabrita, A.R.J.; Fonseca, A.J.M.; Valentão, P.; Andrade, P.B.
Food Chem, 215, 177-184. 2017
Phlorotannins: Towards new pharmacological interventions for diabetes mellitus type 2.
Lopes, G.; Andrade, P.B.; Valentão, P.
Molecules, 22, 56. 2017
Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet.
Gonçalves, S.; Moreira, E.; Grosso, C.; Andrade, P.B.; Valentão, P.; Romano, A.
J Food Sci Technol, 54, 219-227. 2017
Quercus ilex L.: How season, plant organ and extraction procedure can influence chemistry and bioactivities.
Hadidi, L.; Babou, L.; Zaidi, F.; Valentão, P.; Andrade, P.B.; Grosso, C.
Chem Biodivers, 14, e1600187. 2017
HPLC-DAD-ESI/MSn profiling of phenolic compounds from Lathyrus cicero L. seeds.
Ferreres, F.; Magalhães, S.C.Q.; Gil-Izquierdo, A.; Valentão, P.; Cabrita, A.R.J.; Fonseca, A.J.M.; Andrade, P.B.
Food Chem, 214, 678-685. 2017
Alkaloids in the valorization of European Lupinus spp. seeds crop.
Magalhães, S.C.Q.; Fernandes, F.; Cabrita, A.R.J.; Fonseca, A.J.M.; Valentão, P.; Andrade, P.B.
Industrial Crops and Products, 95, 286-295. 2017
Accumulation of primary and secondary metabolites in edible jackfruit seed tissues and scavenging of reactive nitrogen species
Fernandes F, Ferreres F, Gil-Izquierdo A, Oliveira A, Valentão P, Andrade PB. .
Food Chem, 233, 85-95. 2017
Spontaneous variation regarding grape berry skin color: A comprehensive study of berry development by means of biochemical and molecular markers
Ferreira V,; Fernandes F,; Carrasco D,; Hernandez MG,; Pinto-Carnide O,; Arroyo-García R, et al.
Food Res Int, 97, 149-161. 2017
Fatty acid patterns of the edible kelps Saccharina latissima, Sacchoriza polyschides and Laminaria ochroleuca : influence of changing environmental conditions.
Barbosa M,; Fernandes F, ; Pereira DM, ; Azevedo IC, ; Sousa-Pinto I, ; Andrade PB, et al.
Arab J Chem, (in press) Doi:10.1016/j.arabjc.2017.01.015
Exploratory studies on the in vitro anti-inflammatory potential of two herbal teas ( Annona muricata L. and Jasminum grandiflorum L.), and relation with their phenolic composition.
Oliveira AP,; Sá I, ; Pereira DM, ; Gonçalves RF, ; Andrade PB, ; Valentão P.
Chem Biodivers, 14, e1700002. 2017
Inhibition of α-glucosidase and α-amylase by Spanish extra virgin olive oils: the involvement of bioactive compounds other than oleuropein and hydroxytyrosol.
Collado-González J, ; Grosso C,; Valentão P,; Andrade PB,; Ferreres F,; Durand T, et al.
Food Chem, 235, 298-307. 2017
UHPLC-MS/MS profiling of Aplysia depilans and assessment of its potential therapeutic use: Interference on iNOS expression in LPS-stimulated RAW 264.7 macrophages and caspase-mediated pro-apoptotic effect on SH-SY5Y cells.
Pereira RB,; Pinto DCGA,; Pereira DM,; Gomes NGM,; Silva AMS,; Andrade PB, et al.
J Funct Foods, 37, 164-175. 2017
Neurotoxicity of the steroidal alkaloids tomatine and tomatidine is RIP1 kinase- and caspase-independent and involves the eIF2α branch of the endoplasmic reticulum.
da Silva DC,; Andrade PB,; Valentão P,; Pereira DM
J Steroid Biochem Mol Biol, 171, 178-186. 2017
In vitro anti-inflammatory and cytotoxic effects of aqueous extracts from the edible sea anemones Anemonia sulcata and Actinia equina .
Silva TC,; Andrade PB,; Paiva-Martins F,; Valentão P,; Pereira DM.
Int J Mol Sci, 18, 653-669. 2017
Toxicity of phenolipids: protocatechuic acid alkyl esters trigger disruption of mitochondrial membrane potential and caspase activation in macrophages.
Pereira DM,; Silva TC,; Lousada-Barreiro S,; Valentão P,; Paiva-Martins F,; Andrade PB.
Chem Phys Lipids, 206, 16-27. 2017
Anti-inflammatory properties of the stem bark from the herbal drug Vitex peduncularis Wall. ex Schauer and characterization of its polyphenolic profile.
Ferreres F,; Duangsrisai S,; Gomes NGM,; Suksungworn R,; Pereira DM,; Gil-Izquierdo A., et al.
Food Chem Toxicol, 106, 8-16. 2017
Synthesis and preliminary biological evaluation of new phenolic and catecholic dehydroamino acid derivatives.
Monteiro LS,; Oliveira S,; Paiva-Martins F,; Ferreira PMT,; Pereira DM,; Andrade PB, et al.
Tetrahedron, 73, 6199-6209. 2017
Further insights on tomato plant: cytotoxic and antioxidant activity of leaf extracts in human gastric cells.
Figueiredo-González M,; Valentão P,; Pereira,; DM,; Andrade PB.
Food Chem Toxicol, 109, 386-392. 2017
Phlorotannin extracts from Fucales: marine polyphenols as bioregulators engaged in inflammation-related mediators and enzymes.
Barbosa M,; Lopes G,; Ferreres F,; Andrade PB,; Pereira DM,; Gil-Izquierdo Á, et al.
Algal Res, 28, 1-8. 2017
Medicinal species as MTDLs: Turnera diffusa Willd. Ex Schult inhibits CNS enzymes and delays glutamate excitotoxicity in SH-SY5Y cells via oxidative damage.
Bernardo J,; Ferreres F,; Gil-Izquierdo Á,; Valentão P,; Andrade PB.
Food Chem Toxicol, 106, 8-16. 2017
Apparent digestibility coefficients of European grain legumes in rainbow trout ( Oncorhynchus mykiss ) and Nile tilapia ( Oreochromis niloticus )
Magalhães SCQ,; Cabrita ARJ,; Valentão P,; Andrade PB,; Rema P,; Maia MRG,; et al.
Aquac Nutr, 24, 332-340. 2017
Optimization of the recovery of high-value compounds from pitaya fruit by-products using microwave-assisted extraction.
Ferreres F,; Grosso C,; Gil-Izquierdo A,; Valentão P,; Mota AT,; Andrade PB.
Food Chem, 230, 463-474. 2017
Inhibition of α-glucosidase and α-amylase by Spanish extra virgin olive oils: the involvement of bioactive compounds other than oleuropein and hydroxytyrosol.
Collado-González J,; Grosso C,; Valentão P,; Andrade PB,; Ferreres F,; Durand T, et al.
Food Chem, 235, 298-307. 2017
Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria.
Oliveira P, Teixeira J, Oliveira C, Amorim R, Cágide F, Garrido J, et al.
Sci Rep, 7, 6842. 2017
Development of a mitochondriotropic antioxidant based on caffeic acid: proof of concept on celular and mitochondrial oxidative stress models.
Teixeira J,; Cagide F,; Benfeito S,; Soares P,; Garrido J,; Baldeiras I, et al.
J Med Chem, 60, 7084-7098. 2017

2016

Tomato plant leaves: From by-products to the management of enzymes in chronic diseases.
Figueiredo-González, M.; Valentão, P.; Andrade, P.B.
Ind Crop Prod, 94, 621-629. 2016
The pigments of kelps (Ochrophyta) as part of the flexible response to highly variable marine environments.
Fernandes, F.; Barbosa, M.; Oliveira, A.P.; Azevedo, I.C.; Sousa-Pinto, I.; Valentão, P.; Andrade, P.B.
J Appl Phycol, 28, 3689-3696. 2016
Measuring the health-related Sustainable Development Goals in 188 countries: A baseline analysis from the Global Burden of Disease Study 2015.
Lim, S.S.; (…); Pereira, D.M. et al.
The Lancet, 388, 1813-1850. 2016
Global, regional and national levels of maternal mortality, 1990 to 2015: a systematic analysis for the Global Burden of Diseases Study 2015.
Kassebaum, N.J.; (…); Pereira, D.M. et al.
The Lancet, 388, 1775-1812. 2016
Global, regional, national and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality during 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Wang, H.; (…); Pereira, D.M. et al.
The Lancet, 388, 1725-1774. 2016
Global, regional and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Forouzanfar, M.H.; (…); Pereira, D.M. et al.

The Lancet, 388, 1659-1724. 2016
Global, regional and national disability-adjusted life years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2015 Study.
Kassebaum, N.J.; (…); Pereira, D.M. et al.
The Lancet, 388, 1603-1658. 2016
Global, regional, and national incidence, prevalence, and YLDs for 310 acute and chronic diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Vos, T.; (…); Pereira, D.M. et al.
The Lancet, 388, 1545-1602. 2016
Global, regional, and national life expectancy, all-cause and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Wang, H.; (…); Pereira, D.M. et al.
The Lancet, 388, 1459-1544. 2016
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
Wang, H.; (…); Pereira, D.M. et al.
The Lancet HIV, 3, e361-e387. 2016
Evaluation of antioxidant, anticholinesterase, and antidiabetic potential of dry leaves and stems in Tamarix aphylla growing wild in Tunisia.
Mahfoudhi, A.; Grosso, C.; Gonçalves, R.F.; Khelifi, E.; Hammami, S.; Achour, S.; Trabelsi-Ayadi, M.; Valentão, P.; Andrade, P.B.; Mighri, Z.
Chem Biodivers, 13, 1747-1755. 2016
Flavonoids in neurodegeneration: Limitations and strategies to cross CNS barriers.
Andrade, P.B., Grosso, C., Valentao, P., Bernardo, J.
Cur Med Chem, 23, 4151-4174. 2016
Bioactive natural products from Piper betle L. leaves and their α-glucosidase inhibitory potential.
Oliveira, A.P.; Ferreira, J.G.; Riboira, S.; Andrade, P.B.; Valentão, P.
Rec Nat Prod, 10, 771-781. 2016
Fatty acid patterns of the kelps Saccharina latissima, Saccorhiza polyschides and Laminaria ochroleuca: Influence of changing environmental conditions.
Barbosa, M.; Fernandes, F.; Pereira, D.M.; Azevedo, I.C.; Sousa-Pinto, I.; Andrade, P.B.; Valentão, P.
Arabian Journal of Chemistry, in press
Study of phenolic composition and antioxidant activity of myrtle leaves and fruits as a function of maturation.
Babou, L.; Hadidi, L.; Grosso, C.; Zaidi, F.; Valentão, P.; Andrade, P.B.
Eur Food Res Technol, 242, 1447-1457. 2016
Isolation of cells specialized in anticancer alkaloid metabolism by fluorescence-activated cell sorting.
Carqueijeiro, I.; Guimarães, A.L.; Bettencourt, S.; Martínez-Cortés, T.; Guedes, J.G.; Gardner, R.; Lopes, T.; Andrade, C.; Bispo, C.; Martins, N.P.; Andrade, P.; Valentão, P.; Valente, I.M.; Rodrigues, J.A.; Duarte, P.; Sottomayor, M.
Plant Physiol, 171, 2371-2378. 2016
Relationships of Echium plantagineum L. bee pollen, dietary flavonoids and their colonic metabolites with cytochrome P450 enzymes and oxidative stress.
Sousa, C.; Andrade, P.B.; Valentão, P.
RSC Advances, 8, 6084-6092. 2016
Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease.
Pinho, B.R.; Reis, S.D.; Guedes-Dias, P.; Leitão-Rocha, A.; Quintas, C.; Valentão, P.; Andrade, P.B.; Santos, M.M.; Oliveira, J.M.A.
Pharmacol. Res. 103, 328-339. 2016
α-Glucosidase and α-amylase inhibitors from Myrcia spp.: A stronger alternative to acarbose?
Figueiredo-González, M.; Grosso, C.; Valentão, P.; Andrade, P.B.
J Pharmaceut Biomed. 118, 322-327. 2016
Chemical diversity and biological properties of secondary metabolites from sea hares of Aplysia Genus.
Pereira, R.B.; Andrade, P.B.; Valentão, P.
Mar. Drugs, 14, 39. 2016.
Rhizobium as plant probiotic for strawberry production under microcosm conditions.
Flores-Félix, J.-D.; Marcos-García, M.; Silva, L.R.; Menéndez, E.; Martínez-Molina, E.; Mateos, P.F.; Velázquez, E.; García-Fraile, P.; Andrade, P.; Rivas, R.
Symbiosis. 1, 25-32. 2016
Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: findings from the Global Burden of Disease 2013 Study.
Kyu, H.H., (…) Pereira, DM. et al.
JAMA Pediat. 170, 267-287. 2016
Identification of Vitis vinifera L. grape berry skin color mutants and polyphenolic profile.
Ferreira, V.; Fernandes, F.; Pinto-Carnide, O.; Valentão, P.; Falco, V.; Martin, J.P.; Ortiz, J.M.; Arroyo-Garcia, R.; Andrade, P.B.; Castro, I.
Food Chemistry, 194, 117-127, 2016
Biologically active oxylipins from enzymatic and nonenzymatic routes in macroalgae.
Barbosa, M., Valentão, P.; Andrade, P.B.
Mar. Drugs, 14, 23. 2016

2015

Effect of solvent system on extractability of lipidic components of Scenedesmus obliquus (M2-1) and Gloeothece sp. on antioxidant scavenging capacity thereof
Amaro, H.M.; Fernandes, F.; Valentão, P.; Andrade, P.B.; Sousa-Pinto, I.; Malcata, F.X.; et al.
Marine Drugs. 13, 6453-71. 2015
Cork extracts reduce UV-mediated DNA fragmentation and cell death
Araújo, A.R.; Pereira, D.M.; Aroso, I.; Santos, T.; Batista, M.T.; Cerqueira, M.; et al.
RSC Advances. 5, 96151-7. 2015
Antioxidant and proapoptotic activities of Sclerocarya birrea [(A. Rich.) Hochst.] methanolic root extract on the hepatocellular carcinoma cell line HepG2.
Armentano, M.F.; Bisaccia, F.; Miglionico, R.; Russo, D.; Nolfi, N.; Carmosino, M.; Andrade, P.B.; Valentão, P.; et al.
BioMed Research International, ID 561589. 2015
Nonenzymatic α-linolenic acid derivatives from the Sea: macroalgae as novel sources of phytoprostanes
Barbosa, M.; Collado-González, J.; Andrade, P.B.; Ferreres, F.; Valentão, P.; Galano J-M, et al.
J. Agric. Food Chem. 63, 6466-74. 2015
Comparing the phenolic profile of Pilocarpus pennatifolius Lem. by HPLC–DAD–ESI/MSn with respect to authentication and enzyme inhibition potential.
Ferreres, F.; Grosso, C.; Gil-Izquierdo, A.; Fernandes, A.; Valentão, P.; Andrade, P.B.
Ind. Crop Prod. 77, 391-401. 2015
Alternative and efficient extraction methods for marine-derived compounds.
Grosso, C.; Valentão, P.; Ferreres, F.; Andrade, P.B.
Marine Drugs. 13, 3182-230. 2015
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
Naghavi, M.; Wang, H.; (…) Pereira, D.M.; et al.
Lancet. 385, 117-71. 2015
Digestive gland from Aplysia depilans Gmelin: Leads for inflammation treatment
Oliveira, A.P.; Lobo-da-Cunha, A.; Taveira, M.; Ferreira, M.; Valentão, P.; Andrade, P.B.
Molecules. 20, 15766-80. 2015
A comprehensive view of the neurotoxicity mechanisms of cocaine and ethanol
Pereira, R.B.; Andrade, P.B.; Valentão, P.
Neurotox Res. 28, 253-67. 2015
Zinc accumulation and tolerance in Solanum nigrum are plant growth dependent.
Samardjieva, K.A.; Gonçalves, R.F.; Valentão, P.; Andrade, P.B.; Pissarra, J.; Pereira, S. et al.
Int. J. Phytoremed. 17, 272-279. 2015
Global, regional, and national incidence, prevalence, and YLDs for 301 acute and chronic diseases and injuries for 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Vos, T.; Barber, R.M.; (…) Pereira, D.M. et al.
The Lancet, http://dx.doi.org/10.1016/S0140-6736(15)60692-4. 2015
Volatile phenols depletion in red wine using molecular imprinted polymers.
Teixeira, R.; Dopico-García, S.; Andrade, P.B.; Valentão, P.; López-Vilariño, J.M.; González-Rodríguez, V.; Cela-Pérez, C.; Silva, L.R.
J. Food Sci. Technol. DOI: 10.1007/s13197-015-1892-2. 2015
Pennyroyal and gastrointestinal cells: multi-target protection of phenolic compounds against t-BHP-induced toxicity.
Ferreres, F.; Bernardo, J.; Andrade, P.B.; Sousa, C.; Gil-Izquierdo, A.; Valentão, P.
RSC Adv. 5, 41576-41584. 2015
Translating endoplasmic reticulum biology into clinic: a role for ER-targeted natural products?
Pereira, D.M.; Valentão, P.; Correia-da-Silva, G.; Teixeira, N.; Andrade, P.B.
Natural Products Reports. 2015
DOI: 10.1039/C4NP00102H
Effects of colored and non-colored phenolics of Echium plantagineum L. bee pollen in Caco-2 cells under oxidative stress induced by tert-butyl hydroperoxide.
Sousa, C.; Moita, E.; Valentão, P.; Fernandes, F.; Monteiro, P.; Andrade, P.B.
J. Agric. Food Chem. 63, 2083-2091. 2015
Antioxidant and proapoptotic activities of Sclerocarya birrea [(A. Rich.) Hochst] methanolic root extract on the hepatocellular carcinoma cell line HepG2.
Armentano, M.A.; Bisaccia, F.; Miglionico, R.; Russo, D.; Nolfi, N.; Carmosino, M.; Andrade, P.B.; Valentao, P.; Diop, M.S.; Milella, L.
Biomed Res. Int. 2015
(Article ID 561589)
Fatty acids from edible sea hares: anti-inflammatory capacity in LPS-stimulated RAW 264.7 cells involves iNOS modulation.
Pereira, R.B.; Taveira, M.; Valentão, P.; Sousa, C.; Andrade, P.B.
RSC Adv. 5, 8981-8987. 2015
HPLC-DAD analysis and in vitro enzyme inhibition: an integrated approach to predict herbal binary mixtures behaviour employing median effect equation.
Grosso, C.; Valentão, P.; Andrade, C.; Andrade, P.B.
Microchem. J. 119, 176-182. 2015
Beverages of lemon juice and exotic noni and papaya with potential for anticholinergic effects.
Gironés-Vilaplana, A.; Valentão, P.; Andrade, P.B.; Ferreres, F.; Moreno, D.A.; García-Viguera, C.
Food Chem. 170, 16-21. 2015

2014

Nano- and microdelivery systems for marine bioactive lipids.
David M. Pereira, Patrícia Valentão, Paula B. Andrade.
Marine Drugs, 12, 6014-6027. 2014
Bioactive compounds from macroalgae in the new millennium: Implications in neurodegenerative diseases.
Barbosa, M.; Valentão, P.; Andrade, P.B.
Marine Drugs 12: p. 4934-4972. 2014
Piper betle leaves: Profiling phenolic compounds by HPLC-DAD-ESI/MSn and anti-cholinesterase activity.
Ferreres, F.; Oliveira, A.P.; Gil-Izquierdo, A.; Valentão, P.; Andrade, P.B.
Phytochem. Anal. 25, 453-460. 2014
Effects of Echium plantagineum L. bee pollen on basophil degranulation: relationship with metabolic profile.
Moita, E.; Sousa, C.; Andrade, P.B.; Fernandes, F.; Pinho, B.; Silva, L.R.; Valentão, P.
Molecules 19, 10635-10649. 2014
Marine natural pigments: chemistry, distribution and analysis.
Pereira, D.M.; Valentão, P.; Andrade, P.B.
Dyes Pigments 111, 124-134. 2014
Box-Behnken factorial design to obtain a phenolic-rich extract from the aerial parts of Chelidonium majus L.
Grosso, C.; Ferreres, F.; Gil-Izquierdo, A.; Valentão, P.; Sampaio, M.; Lima, J.; Andrade, P.B.
Talanta 130, 128-136. 2014
Phenolic profile of Douro wines and evaluation of their ●NO scavenging capacity in LPS-stimulated RAW 264.7 macrophages.
Rebelo, M.J.; Sousa, C.; Valentão, P.; Rego, R.; Andrade, P.B.
Food Chem. 163, 16-22. 2014
GC-MS lipidomic profiling of the echinoderm Marthasterias glacialis and screening for activity against human cancer and non-cancer cell lines.
Pereira, D.M.; Correia-da-Silva, G.; Valentão, P.; Teixeira, N.; Andrade, P.B.
Comb. Chem. High Throughput Screen. 17, 450-457. 2014
Bioactive marine drugs and marine biomaterials for brain diseases. Grosso, C.; Valentão, P.; Ferreres, F.; Andrade, P.B.
Mar. Drugs 12, 2539-2589. 2014
Effects of chlorophenoxy herbicides and their main transformation products on DNA damage and acetylcholinesterase activity.
Benfeito, S.; Silva, T.; Garrido, J.; Andrade, P.B.; Sottomayor, M.J.; Borges, F.; Garrido, M.E.
BioMed Res. Int. vol. 2014, Article ID 709036, 10 pages. doi:10.1155/2014/709036. 2014
Anti-inflammatory potential of monogalactosyl diacylglycerols and a monoacylglycerol from the edible brown seaweed Fucus spiralis Linnaeus.
Lopes, G.; Daletos, G.; Proksch, P.; Andrade, P.B.; Valentão, P.
Mar. Drugs 12, 1406-1418. 2014
Modulation of basophils' degranulation and allergy-related enzymes by monomeric and dimeric naphthoquinones.
Pinho, B.R.; Sousa, C.; Valentão, P.; Oliveira, J.M.A.; Andrade, P.B.
PLoS ONE 9(2): e90122. 2014
HPLC-DAD-ESI/MSⁿ analysis of phenolic compounds for quality control of Grindelia robusta Nutt. and bioactivities.
Ferreres, F.; Grosso, C.; Gil-Izquierdo, A.; Valentão, P.; Azevedo, C.; Andrade, P.B.
J. Pharm. Biomed. Anal. 94, 163-172. 2014
Inoculation of the non-legume Capsicum annuum (L.) with Rhizobium strains: Part 1. Effect on bioactive compounds, antioxidant activity and fruit ripeness.
Silva, L.R.; Azevedo, J.; Pereira, M.J.; García, L.; Velazquez, E.; Peix, A.; Valentão, P.; Andrade, P.B.
J. Agric. Food Chem. 62, 557-564. 2014
Inoculation of the non-legume Capsicum annuum (L.) with Rhizobium strains: Part 2. Changes on sterols, triterpenes, fatty acids and volatile compounds.
Silva, L.R.; Azevedo, J.; Pereira, M.J.; García, L.; Velazquez, E.; Peix, A.; Valentão, P.; Andrade, P.B.
J. Agric. Food Chem. 62, 565-573. 2014
Anti-inflammatory effect of unsaturated fatty acids and ergosta-7,22-dien-3-ol from Marthasterias glacialis: prevention of CHOP-mediated ER-stress and NF-κB activation.
Pereira, D.M.; Correia-da-Silva, G.; Valentão, P.; Teixeira, N.; Andrade, P.B.
PLoS ONE 9(2): e88341. 2014
Neuroprotective effect of steroidal alkaloids on glutamate-induced toxicity by preserving mitochondrial membrane potential and reducing oxidative stress.
Taveira, M.; Sousa, C.; Valentão, P.; Ferreres, F.; Teixeira, J.P.; Andrade, P.B.
J. Steroid Biochem. Mol. Biol. 140, 106-115. 2014
Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells.
Pereira, D.M.; Correia-da-Silva, G.; Valentão, P.; Teixeira, N.; Andrade, P.B.
Mar. Drugs 12, 54-68. 2014
Assessing Jasminum grandiflorum L. authenticity by HPLC-DAD-ESI/MSn and effects on physiological enzymes and oxidative species.
Ferreres, F.; Grosso, C.; Gil-Izquierdo, A.; Valentão, P.; Andrade, P.B.
J. Pharm. Biomed. Anal. 88, 157-161. 2014

2013

Antifungal activity of phlorotannins against dermatophytes and yeasts: approaches to the mechanism of action and influence on Candida albicans virulence factor.
Lopes, G.; Pinto, E.; Andrade, P.B.; Valentão, P.
PLoS ONE 8(8): e72203. 2013
Inoculation with Bradyrhizobium japonicum enhances the organic and fatty acids content of soybean (Glycine max (L.) Merrill) seeds.
Silva, L.R.; Pereira, M.J.; Azevedo, J.; Mulas, R.; Velazquez, E.; González-Andrés, F.; Valentão, P.; Andrade, P.B.
Food Chem. 141, 3636-3648. 2013
A new iced tea base herbal beverage with Spergularia rubra extract: metabolic profile stability and in vitro enzyme inhibition.
Oliveira, A.P.; Matos, R.P.; Silva, S.T.; Andrade, P.B.; Ferreres, F.; Gil-Izquierdo, A.; Meireles, S.; Brandão, T.M.; Valentão, P.
J. Agric. Food Chem. 61, 8650−8656. 2013
Glutathione and the antioxidant potential of binary mixtures with flavonoids: Synergisms and antagonisms.
Pereira, R.B.; Sousa, C.; Costa, A.; Andrade, P.B.; Valentão, P.
Molecules 18, 8858-8872. 2013
Influence of taro (Colocasia esculenta L. Shott) growth conditions on the phenolic composition and biological properties.
Gonçalves, R.F.; Silva, A.M.S.; Silva, A.M.; Valentão, P.; Ferreres, F.; Gil-Izquierdo, A.; Silva, J.B.; Santos, D.; Andrade, P.B.
Food Chem. 141, 3480-3485. 2013
Amino acids, fatty acids and sterols profile of some marine organisms from Portuguese waters.
Pereira, D.M.; Valentão, P.; Teixeira, N.; Andrade, P.B.
Food Chem. 141,2412-2417.2013
Metabolic profile and biological activities of Lavandula pedunculata subsp. lusitanica (Chaytor) Franco: studies on the essential oil and polar extracts.
Costa, P.; Gonçalves, S.; Valentão, P.; Andrade, P.B.; Almeida, C.; Nogueira, J.M.F.; Romano, A.
Food Chem. 141, 2501 - 2506. 2013
How mitochondrial dysfunction affects zebrafish development and cardiovascular function: An in vivo model for testing mitochondria-targeted drugs.
Pinho, B.R.; Santos, M. M.; Fonseca-Silva, A.; Valentão, P.; Andrade, P.B.; Oliveira, J.M.A.
Br. J. Pharmacol. 169, 1072 - 1090. 2013
Nature as source of metabolites with cholinesterases inhibitory activity: an approach to Alzheimer’s disease treatment.
Pinho, B.R.; Ferreres, F.; Valentão, P.; Andrade, P.B.
J. Pharm. Pharmacol. 65, 1681-1700. 2013
Alzheimer disease and antioxidant therapy: How long how far?
Teixeira, J.; Silva, T.; Andrade, P.B.; Borges, F.
Curr. Med. Chem. 20, 2939-2952. 2013
The use of flavonoids in central nervous system disorders
Grosso, C.; Valentão, P.; Ferreres, F.; Andrade, P.B.
Curr. Med. Chem. 20, 4694-4719. 2013
Ellagic acid and derivatives from Cochlospermum angolensis Welw. extracts: HPLC-DAD-ESI/MSn profiling, quantification and in vitro antidepressant, anticholinesterase and antioxidant activities.
Ferreres, F.; Grosso, C.; Gil-Izquierdo, A.; Valentão, P.; Andrade, P.B.
Phytochem. 24, 534-540. 2013
Effect of different extraction methodologies on the recovery of bioactive metabolites from Satureja parvifolia (Phil.) Epling (Lamiaceae).
Cabana, R.; Silva, L.R.; Valentão, P.; Viturro, C.I.; Andrade, P.B.
Ind. Crops Prod. 48, 49-56. 2013
Accumulation of phenolic compounds in in vitro cultures and wild plants of Lavandula viridis L'Hér and their antioxidant and anti-cholinesterase potential.
Costa, P.; Gonçalves, S.; Valentão, P.; Andrade, P.B.; Romano, A.
Food Chem. Toxicol. 57, 69-74. 2013
Phenolic compounds from Jacaranda caroba (Vell.) A. DC.: approaches to neurodegenerative disorders.
Ferreres, F.; Grosso, C.; Gil-Izquierdo, A.; Valentão, P.; Andrade, P.B.
Food Chem. Toxicol. 57, 91-98. 2013
Integrated analysis of COX-2 and iNOS derived inflammatory mediators in LPS-stimulated RAW macrophages pre-exposed to Echium plantagineum L. bee pollen extract.
Moita, E.; Gil-Izquierdo, A.; Sousa, C.; Ferreres, F.; Silva, L.R.; Valentão, P.; Domínguez-Perles, R.; Baenas, N.; Andrade, P.B.
PLoS ONE 8(3): e59131. 2013.
Valuable compounds in macroalgae extracts.
Andrade, P.B.; Barbosa, M.; Matos, R.P.; Lopes, G., Vinholes, J.; Mouga, T.; Valentão, P.
Food Chem. 138, 1819-1828. 2013.
Chemical assessment and antioxidant capacity of pepper (Capsicum annuum L.) seeds.
Silva, L.R.; Azevedo, J.; Pereira, M.J:; Valentão, P.; Andrade, P.B.
Food Chem. Toxicol. 53, 240-248. 2013.
Glycine max (L.) Merr., Vigna radiate L. and Medicago sativa L. sprouts: A natural source of bioactive compounds.
Silva, L.R.; Pereira, M.J.; Azevedo, J.; Gonçalves, R.F.; Valentão, P.; Guedes de Pinho, P.; Andrade, P.B.
Food Res. Int. 50, 165-175. 2013
Vitis vinifera leaves towards bioactivity.
Fernandes, F.; Ramalhosa, E.; Pires, P.; Bento, A.; Verdial, J.; Valentão, P.; Andrade, P.B.; Pereira, J.P.
Ind. Crops Prod. 43, 434-440. 2013
Influence of solvent on the antioxidant and antimicrobial properties of walnut (Juglans regia L.) green husk extracts.
Fernández-Agulló, A.; Pereira, E.; Freire, M.S.; Valentão, P.; Andrade, P.B.; González-Álvarez, J.; Pereira, J.A.
Ind. Crops Prod. 42, 126-132. 2013
In vitro studies of α-glucosidase inhibitors and antiradical constituents of Glandora diffusa (Lag.) D. C. Thomas infusion. Ferreres, F.; Vinholes, J.; Gil-Izquierdo, A.; Valentão, P.; Gonçalves, R.F.; Andrade, P.B.
Food Chem. 136, 1390-1398. 2013
Changes on organic acid secretion and accumulation in Plantago almogravensis Franco and Plantago algarbiensis Samp. under aluminum stress. Martins, N.; Gonçalves, S.; Andrade, P.B.; Valentão, P.; Romano, A.
Plant Sci. 198, 1-6. 2013

2012

Phlorotannins extracts from Fucales characterized by HPLC-DAD-ESI-MSn: Approaches to hyaluronidase inhibitory capacity and antioxidant properties.
Ferreres, F.; Lopes, G.; Gil-Izquierdo, A.; Andrade, P.B.; Sousa, C.; Mouga, T.; Valentão, P.
Mar. Drugs 10, 2766-2781. 2012
A gas chromatography-mass spectrometry multi-target method for the simultaneous analysis of three classes of metabolites in marine organisms.
Pereira, D.M.; Vinholes, J.; Guedes de Pinho, P.; Valentão, P.; Mouga, T.; Teixeira, N.; Andrade, P.B.
Talanta 100, 391-400. 2012
Characterization of Ficus carica L. cultivars by DNA and secondary metabolites analysis: Is genetic diversity reflected in the chemical composition?
Oliveira, A.P.; Baptista, P.; Andrade, P.B.; Martins, F.; Pereira, J.A.; Silva, B.M.; Valentão, P.
Food Res. Int. 49, 710-719. 2012
Further insights on the carotenoid profile of the echinoderm Marthasterias glacialis L.
Mariutti, L.R.B.; Pereira, D.M.; Mercadante, A.Z.; Valentão, P.; Teixeira, N.; Andrade, P.B.
Mar. Drugs 10, 1498-1510. 2012
Further knowledge on the phenolic profile of Colocasia esculenta (L.) Shott.
Ferreres, F.; Gonçalves, R.F.; Gil-Izquierdo, A.; Valentão, P.; Silva, A.M.S.; Silva, J.B.; Santos, D.; Andrade, P.B.
J. Agric. Food Chem. 60, 7005-7015. 2012.
Thymus lotocephalus wild plants and in vitro cultures produce different profiles of phenolic compounds with antioxidant activity.
Costa, P.; Gonçalves, S.; Valentão, P.; Andrade, P.B.; Coelho, N.; Romano, A.
Food Chem. 135, 1253-1260. 2012.
New beverages of lemon juice enriched with the exotic berries Maqui, Açaí, and Blackthorn: bioactive components and in vitro biological properties.
Girones-Vilaplana, A.; Valentão, P.; Moreno, D.A.; Ferreres, F.; Garcia-Viguera, C.; Andrade, P.B.
J. Agric. Food Chem. 60, 6571-6580. 2012.
Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosa L.) inflorescences.
Silva, L.R.; Valentão, P.; Faria, J.; Ferreres, F.; Sousa, C.; Gil-Izquierdo, A.; Pinho, B.; Andrade, P.B.
Food Chem. 135, 756-763. 2012
Fast determination of bioactive compounds from Lycopersicon esculentum Mill. leaves.
Taveira, M.; Ferreres, F.; Gil-Izquierdo, A.; Oliveira, L.; Valentão, P.; Andrade, P.B.
Food Chem. 135, 748-755. 2012
Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér. Costa, P.; Grosso, C.; Gonçalves, S.; Andrade, P.B.; Valentão, P.; Bernardo-Gil, M.G.; Romano, A.
Food Chem. 135, 112-121. 2012
Brassica oleracea L. var. costata DC and Pieris brassicae L. aqueous extracts reduce methyl methanesulfonate-induced DNA damage in V79 hamster lung fibroblasts.
Sousa, C.; Fernandes, F.; Valentão, P.; Rodrigues, A.S.; Coelho, M.; Teixeira, J.P.; Silva, S.; Ferreres, F.; Guedes de Pinho, P.; Andrade, P.B.
J. Agric. Food Chem. 60, 5380-5387. 2012
Phytochemical profile of a blend of black chokeberry and lemon juice with cholinesterase inhibitory effect and antioxidant potential.
Girones-Vilaplana, A.; Valentão, P.; Andrade, P.B.; Ferreres, F.; Moreno, D.A.; Garcia-Viguera, C.
Food Chem. 134, 2090-2096. 2012
Kale extract increases glutathione levels in V79 cells, but does not protect them against acute toxicity induced by hydrogen peroxide.
Fernandes, F.; Sousa, C.; Ferreres, F.; Valentão, P.; Remião, F.; Pereira J.A., Andrade, P.B.
Molecules 17, 5269-5288. 2012
Targeted metabolites and biological activities of Cydonia oblonga Miller leaves.
Oliveira, A.P.; Costa, R.M.; Magalhães, A.S.; Pereira, J.A.; Carvalho, M.; Valentão, P.; Andrade, P.B.; Silva, B.M.
Food Res. Int. 46, 496-504. 2012
Bauhinia forficata Link authenticity using flavonoids profile: relation with their biological properties.

Plant secondary metabolites in cancer chemotherapy: where are we?

Can phlorotannins purified extracts constitute a novel pharmacological alternative for microbial infections with associated inflammatory conditions?

Chemical profiling and biological screening of Thymus lotocephalus extracts obtained by supercritical fluid extraction and hydrodistillation.

Assessing the anthocyanic composition of Port wines and musts and their free radical scavenging capacity.

Assessing Rubus honey value: pollen and phenolic compounds content and antibacterial capacity.

2011

Structural characterization of phenolics and betacyanins in Gomphrena globosa by high-performance liquid chromatography-diode array detection-electrospray ionization multi-stage mass spectrometry.
Ferreres, F.; Gil-Izquierdo, A.; Valentão, P.; Andrade, P.B.
Rapid Communn. Mass Spectrom. 25, 3441-3446. 2011
Sterol profiles in 18 macro algae of the Portuguese coast.
Lopes, G.; Sousa, C.; Bernardo, J.; Ferreres, F.; Andrade, P.B.; Mouga, T.; Valentão, P.
J. Phycol. 47, 1210-1218. 2011.
Is nitric oxide decrease observed with naphthoquinones in LPS stimulated RAW 264.7 macrophages a beneficial property?
Pinho, B.R.; Sousa, C.; Valentão, P.; Andrade, P.B.

PLoS ONE 6(8): e24098. 2011
In vitro studies to assess the antidiabetic, anti-cholinesterase and antioxidant potential of Spergularia rubra.
Vinholes, J.; Grosso, C.; Andrade, P.B.; Gil-Izquierdo, A.; Valentão, P.; Guedes de Pinho, P.; Ferreres, F.
Food Chem. 129, 454-462. 2011.
Dracaena draco fruit: phytochemical and antioxidant activity assessment.
Silva, B.M.; Santos, R.P.; Mendes, L.S.; Guedes de Pinho, P.; Valentão, P.; Andrade, P.B.; Pereira, J.A.; Carvalho, M.
Food Res. Int. 44, 2182-2189. 2011
High-performance liquid chromatography-diode array detection-electrospray ionization multi-stage mass spectrometric screening of an insect/plant system: the case of Spodoptera littoralis/Lycopersicon esculentum phenolics and alkaloids.
Ferreres, F.; Taveira, M.; Gil-Izquierdo, A.; Oliveira, L.; Teixeira, T.; Valentão, P.; Simões, N.; Andrade, P.B.
Rapid Communn. Mass Spectrom. 25, 1972-1980. 2011.
Anti-proliferative activity of meroditerpenoids isolated from the brown alga Stypopodium flabelliforme against several cancer cell lines.
Pereira, D.M.; Cheel, J.; Areche, C.; San-Martín, A.; Rovirosa, J.; Silva, L.R.; Valentão, P.; Andrade, P.B.
Mar. Drugs 9, 852-862. 2011.
Fatty acids in marine organisms: In the pursuit of bioactive agents.
Pereira, D.M.; Vinholes, J.; Correia da Silva, G.; Valentão, P.; Teixeira, N.; Andrade, P.B.
Curr. Pharm. Anal. 7, 108-119. 2011.
Effects induced by the nodulation with Bradyrhizobium japonicum on Glycine max (soybean) metabolism and antioxidant potential.
Couto, C.; Silva, L.R.; Valentão, P.; Velázquez, E.; Peix, A.; Andrade, P.B.
Food Chem. 127, 1487-1495. 2011.
Identification of phenolic compounds in isolated vacuoles of the medicinal plant Catharanthus roseus and their interaction with vacuolar class III peroxidase - an H₂O₂ affair?
Ferreres, F.; Figueiredo, R.; Bettencourt, S.; Carqueijeiro, I.; Oliveira, J.; Gil-Izquierdo, A.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Duarte, P.; Ros Barceló, A.; Sottomayor, M.
J. Exp. Bot. 62, 2841-2854. 2011.
Approach to the study of C-glycosyl flavones acylated with aliphatic and aromatic acids from Spergularia rubra by high-performance liquid chromatography-photodiode array detection/electrospray ionization multi-stage mass spectrometry
Ferreres, F.; Gil-Izquierdo, A.; Vinholes, A.; Grosso, C.; Valentão, P.; Andrade, P.B.
Rapid Communn. Mass Spectrom. 25, 700-712. 2011
Inhibitory effect of Lavandula viridis on Fe²⁺-induced lipid peroxidation, and antioxidant and anti-cholinesterase properties.
Costa, P.; Gonçalves, S.; Andrade, P.B.; Valentão, P.; Romano, A.
Food Chem. 126, 1779-1786. 2011
Natural extracts as potential source of antioxidants to stabilize polyolefins.
Dopico-García, M.S.; Castro-López, M.M.; López-Vilariño, J.M.; González-Rodríguez, M.V.; Valentão, P.; Andrade, P.B.; García-Garabal, S.; Abad, M.J.
J. Appl. Polym. Sci. 119, 3553-3559. 2011.
Phytochemical profiles and inhibitory effect on free radical-induced human erythrocyte damage of Dracaena draco leaf: A potential novel antioxidant agent.
Santos, R.P.; Mendes, L.S.; Silva, B.M.; Guedes de Pinho, P.; Valentão, P.; Andrade, P.B.; Pereira, J.A.; Carvalho, M.
Food Chem. 124, 927-934. 2011

2010

Further insights into the latex metabolite profile of Ficus carica.
Oliveira, A.P.; Silva, L.R.; Andrade, P.B.; Valentão, P.; Silva, B.M.; Gonçalves, R.;. Pereira, J.A.;Guedes de Pinho, P.
J. Agric. Food Chem. 58, 10855-10863. 2010.
Improving the knowledge on Piper betle: targeted metabolite analysis and effect on acetylcholinesterase.
Valentão, P.; Gonçalves, R.F.; Belo, C.; Guedes de Pinho, P.; Andrade, P.B.; Ferreres, F.
J. Sep. Sci. 33, 3168-3176. 2010.
Phenolic composition of hazelnut leaves: Influence of cultivar, geographical origin and ripening stage.
Amaral, J.S.; Valentão, P.; Andrade, P.B.; Martins, R.C.; Seabra, R.M.
Sci. Hortic. 126 306-313. 2010
Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.
Taveira, M.; Silva, L.R.; Vale-Silva, L.A.; Pinto, E.; Valentão, P.; Ferreres, F.; Guedes de Pinho, P.; Andrade, P.B.
J. Agric. Food Chem. 58, 9529–9536. 2010
HPLC-PAD-APCI-MS metabolite profiling of cytotoxic carotenoids from the echinoderm Marthastherias glacialis (spiny sea-star).
Ferreres, F.; Pereira, D.M.; Gil-Izquierdo, A.; Valentão, P.; Botelho, J.; Mouga, T.; Andrade, P.B.
J. Sep. Sci. 33, 2250–2257. 2010
Volatile profiling of Ficus carica varieties by HS-SPME and GC-IT-MS.
Oliveira, A.P.; Silva, L.R.; Guedes de Pinho, P.; Gil-Izquierdo, A.; Valentão, P.; Silva, B.M.; Pereira, J.A.; Andrade, P.B.
Food Chem. 123, 548-557. 2010.
Pharmacological effects of Catharantus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission.
Pereira, D.M.; Ferreres, F.; Oliveira, J.M.A.; Gaspar, L.; Faria, J.; Valentão, P.; Sottomayor, M.; Andrade, P.B.
Phytomedicine 17, 646-652. 2010
Green tea: a promising anticancer agent for renal cell carcinoma.
Carvalho, M.; Jerónimo, C.; Valentão, P.; Andrade, P.B.; Silva, B.M.
Food Chem. 122, 49-54. 2010.
Tomato (Lycopersicon esculentum) seeds: new flavonols and cytotoxic effect.
Ferreres, F.; Taveira, M.; Pereira, D.M.; Valentão, P.; Andrade, P.B.
J. Agric. Food Chem. 58, 2854-2861. 2010
Determination of low molecular weight volatiles in Ficus carica using HS-SPME and GC/FID.
Oliveira, A.P.; Silva, L.R.; Andrade, P.B.; Valentão, P.; Silva, B.M.; Pereira, J.A.; Guedes de Pinho, P.
Food Chem. 121, 1289-1295. 2010
Chemical assessment and in vitro antioxidant capacity of Ficus carica latex.
Oliveira, A.P.; Silva, L.R.; Ferreres, F.; Guedes de Pinho, P.; Valentão, P.; Silva, B.M.; Pereira, J.A.; Andrade, P.B.
J. Agric. Food Chem. 58, 3393-3398. 2010
First report on Cydonia oblonga Miller anticancer potential: differential antiproliferative effect against human kidney and colon cancer cells.
Carvalho, M.; Silva, B.M.; Silva, R.; Valentão, P.; Andrade, P.B.; Bastos, M.L.
J. Agric. Food Chem. 58, 3366-3370. 2010
Exploiting Catharanthus roseus roots: source of antioxidants.
Pereira, D.M.; Faria, J.; Gaspar, L.; Ferreres, F.; Valentão, P.; Sottomayor, M.; Andrade, P.B.
Food Chem. 121, 56-61. 2010
First report of non-coloured flavonoids in Echium plantagineum bee pollen: differentiation of isomers by liquid chromatography/ion trap mass spectrometry.
Ferreres, F.; Pereira, D.M.; Valentão, P.; Andrade, P.B.
Rapid Commun. Mass Spectrom. 24, 801-806. 2010
Headspace solid-phase microextraction and gas chromatography/ion trap-mass spectrometry applied to a living system: Pieris brassicae fed with kale.
Fernandes, F.; Pereira, D.M.; Guedes de Pinho, P.; Valentão, P.; Pereira, J.A.; Bento, A.; Andrade, P.B.
Food Chem. 119, 1681-1693. 2010
Codium tomentosum and Plocamium cartilagineum: chemistry and antioxidant potential.
Valentão, P.; Trindade, P.; Gomes, D.; Guedes de Pinho, P.; Mouga, T.; Andrade, P.B.
Food Chem. 119, 1359-1368. 2010
Simple and reproducible HPLC-DAD-ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots.
Ferreres, F.; Pereira, D.M.; Valentão, P.; Oliveira, J. M. A.; Faria, J.; Gaspar, L.; Sottomayor, M.; Andrade, P.B.
J. Pharm. Biomed. Anal. 51, 65-69. 2010.

2009

Ficus carica L.: Metabolic and biological screening.
Oliveira, A.P.; Valentão, P.; Pereira, J.A.; Silva, B.M.; Tavares, F.; Andrade, P.B.
Food Chem. Toxicol. 47, 2841-2846. 2009
Evolution of Brassica rapa var. rapa L. volatile composition by HS-SPME and GC/IT-MS.
Taveira, M.; Fernandes, F.; Guedes de Pinho, P.; Andrade, P.B.; Pereira, J.A.; Valentão, P.
Microchem. J. 93, 140-146. 2009
Phenolics metabolism in insects: Pieris brassicae - Brassica oleracea var. costata ecological duo.
Ferreres, F.; Fernandes, F.; Pereira, D.M.; Pereira, J.A.; Valentão, P.; Andrade, P.B.
J. Agric. Food Chem. 57, 9035-9043. 2009.
Metabolic and bioactivity insights into Brassica oleracea var. acephala.
Ferreres, F.; Fernandes, F.; Sousa C.; Valentão, P.; Pereira, J.A.; Andrade, P.B.
J. Agric. Food Chem. 57, 8884-8892. 2009.
Volatile constituents throughout Brassica oleracea L. var. acephala germination.
Fernandes, F.; Guedes de Pinho, P.; Valentão, P.; Pereira, J.A.; Andrade, P.B.
J. Agric. Food Chem. 57, 6795-6802. 2009.
Water extracts of Brassica oleracea var. costata potentiate paraquat toxicity to rat hepatocytes in vitro.
Sousa, C.; Pontes, H.; Carmo, H.; Dinis-Oliveira R.J.; Valentão, P.; Andrade, P.B.; Remião, F.; Bastos, M.L.; Carvalho, F.
Toxicol. In Vitro. 23, 1131-1138. 2009
Fatty acid composition of wild edible mushrooms species: a comparative study.
Ribeiro, B.; Guedes de Pinho, P.; Andrade, P.B.; Baptista, P.; Valentão, P.
Microchem. J. 93, 29-35. 2009
Determination of eighty-one volatile organic compounds in dietary Rumex induratus leaves by GC/IT-MS, using different extractive techniques.
Taveira, M.; Guedes de Pinho, P.; Gonçalves, R.F.; Andrade, P.B.; Valentão, P.
Microchem. J. 93, 67-72. 2009
Honey from Luso region (Portugal): physicochemical characteristics and mineral contents.
Silva, L.R; Videira, R.; Monteiro, A.P.; Valentão, P.; Andrade, P.B.
Microchem. J. 93, 73-77. 2009
Metabolic fate of dietary volatile compounds in Pieris brassicae.
Fernandes, F.; Pereira, D.M.; Guedes de Pinho, P.; Valentão, P.; Pereira, J.A.; Bento, A.; Andrade, P.B.
Microchem. J. 93, 99-109. 2009
Volatile composition of Brassica oleracea L. var. costata DC leaves using solid phase microextraction and gas chromatography/ion trap mass spectrometry.
Guedes de Pinho, P.; Valentão, P.; Gonçalves, R.F.; Sousa, C.; Seabra, R.M.; Andrade, P.B.
Rapid Commun. Mass Spectrom. 23, 2292-2300. 2009
Phenolics: From chemistry to biology.
Pereira, D.M.; Valentão, P.; Pereira, J.A.; Andrade, P.B.
Molecules, 14, 2202-2211. 2009
Boerhaavia diffusa: metabolite profiling of a medicinal plant from Nyctaginaceae.
Pereira, D.M.; Faria, J.; Gaspar, L.; Valentão, P.; Andrade, P.B.
Food Chem. Toxicol. 47, 2142-2149. 2009
Phytochemical characterization and radical scavenging activity of Portulaca oleraceae L. leaves and stems.
Oliveira, I.; Valentão, P.; Lopes, R.; Andrade, P.B.; Bento, A.; Pereira, J.A.
Microchem. J. 92, 129-134. 2009
Metabolic profiling and biological capacity of Pieris brassicae fed with kale (Brassica oleracea L. var. acephala).
Ferreres, F.; Fernandes, F.; Oliveira, J.M.A.; Valentão, P.; Pereira, J.A.; Andrade, P.B.
Food Chem. Toxicol., 47, 1209-1220. 2009
Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract.
Almeida, I.F.; Fernandes, E.; Lima, J.L.F.C.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Costa, P.C.; Bahia, M.F.
J. Med. Food, 12, 175-183. 2009
Targeted metabolite analysis of Catharanthus roseus and its biological potential.
Pereira, D.M.; Oliveira, J.; Ferreres, F.; Valentão, P.; Andrade, P.B.; Sottomayor, M.
Food Chem. Toxicol. , 47, 1349-1354. 2009
Protective effect of quince (Cydonia oblonga Miller) fruit against oxidative hemolysis of human erythroytes.
Magalhães, A.S.; Silva, B.M.; Pereira, J.A.; Andrade, P.B.; Valentão, P.; Carvalho, M.
Food Chem. Toxicol., 47, 1372-1377. 2009
Brassica oleracea var. costata: comparative study on organic acids and biomass production with other cabbage varieties.
Sousa, C.; Pereira, D.M.; Taveira, M.; Dopico-García, S.; Valentão, P.; Pereira, J.A.; Bento, A.; Andrade, P.B.
J. Sci. Food Agric., 89, 1083-1089. 2009
Improved loquat (Eriobotrya japonica Lindl.) cultivars: variation of phenolics and antioxidative potential.
Ferreres, F.; Gomes, D.; Valentão, P.; Gonçalves, R.; Pio, R.; Alves Chagas, E.; Seabra, R.M.; Andrade, P.B.
Food Chem., 114, 1019-1027. 2009
Targeted metabolite analysis and biological activity of Pieris brassicae fed with Brassica rapa var. rapa.
Pereira, D.M.; Noites, A.; Valentão, P.; Ferreres, F.; Pereira, J.A.; Vale-Silva, L.; Pinto, E.; Andrade, P.B.
J.Agric. Food Chem., 57, 483-489. 2009
Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry.
Guedes de Pinho, P.; Gonçalves, R.F.; Valentão, P.; Pereira, D.M.; Seabra, R.M.; Andrade, P.B.; Sottomayor, M.
J. Pharm. Biomed. Anal., 49, 674-685. 2009
In vitro cultures of Brassica oleracea L. var costata DC: potential plant bioreactor for antioxidant phenolic compounds.
Taveira, M.; Pereira, D.M.; Sousa, C.; Ferreres, F.; Andrade, P.B.; Martins. A.; Pereira, J.A.; Valentão, P. J. Agric. Food Chem., 57, 1247-1252. 2009
Evaluation of free radical scavenging and antihemolytic activities of quince (Cydonia oblonga) leaf: a comparative study with green tea (Camellia sinensis).
Costa, R.M.; Magalhães, A.S.; Pereira, J.A.; Andrade, P.B.; Valentão, P.; Carvalho, M.; Silva, B.M.
Food Chem. Toxicol., 49, 860-865. 2009
Screening of antioxidant phenolic compounds produced by in vitro shoots of Brassica oleraceaL. var. costata DC.
Ferreres, F.; Cousa, C.; Pereira, D. M.; Valentão, P.; Taveira, M.; Martins, A.; Pereira, J. A.; Seabra, R. M.; Andrade, P. B.
Comb. Chem. High Throughput Screen., 12, 125-136. 2009
Pieris brassicae inhibits xanthine oxidase.
Sousa, C.; Pereira, D.M.; Valentão, P.; Ferreres, F.; Pereira, J.A.; Bento, A.; Seabra, R.M.; Andrade, P.B.
J. Agric. Food Chem., 57, 2288-2294. 2009
Free water-soluble phenolics profiling in barley (Hordeum vulgare L.).
Ferreres, F.; Kršková, Z.; Gonçalves, R.F.; Valentão, P.; Pereira, J.A.; Dušek, J.; Martin, J.; Andrade, P.B.
J. Agric. Food Chem., 57, 2405-2409. 2009

2008

New phenolic compounds and antioxidant potential of Catharanthus roseus.
Ferreres, F.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Sottomayor, M.
J. Agric. Food Chem. 56, 9967-9974, 2008
Further knowledge on barley (Hordeum vulgare L.) leaves O-glycosyl-C-glycosyl flavones by liquid chromatography-UV diode array detection-electrospray ionisation mass spectrometry.
Ferreres, F.; Andrade, P.B.;Valentão, P.; Gil-Izquierdo, A.
J. Chromatogr. A, 1182, 56-64, 2008
Tronchuda cabbage (Brassica oleracea L. var. costata DC): scavenger of Reactive Nitrogen Species.
Sousa, C.; Valentão, P.; Ferreres, F.; Seabra, R.M.; Andrade, P.B.
J. Agric. Food Chem., 56, 4205-4211, 2008
HPLC-DAD-MS/MS-ESI Screening of phenolic compounds in Pieris brassicae L. reared on Brassica rapa var rapa
Ferreres, F.; Valentão, P.; Pereira, J.A.; Bento, A.; Noites, A.; Seabra, R.M.; Andrade, P.B.
L. J. Agric. Food Chem., 56, 844-853, 2008
Principal components of phenolics to characterize red Vinho Verde grapes: anthocyanins or non coloured compounds?
Dopico-García MS, Fique A; Guerra L, Afonso JM, Pereira O, Valentão P, Andrade PB, Seabra RM
Talanta, 75, 1190-1202, 2008
Correlation between the pattern volatiles and the overall aroma of wild edible mushrooms
Pinho PG, Ribeiro B, Gonçalves RF, Baptista P, Valentão P, Seabra RM, Andrade PB
J Agric Food Chem., 56:1704-1712, 2008
Multivariate analysis of tronchuda cabbage (Brassica oleraceae L. var costata DC) phenolics: influence of fertilizers
Sousa C, Pereira DM, Pereira JA, Bento A, Rodrigues MA, Dopico-Garcia MS, Valentão P, Lopes G, Ferreres F, Seabra RM, Andrade PB.
J Agric Food Chem., 56: 2231-2239, 2008
Comparative study of phytochemicals and antioxidant potential of wild edible mushrooms cap and stipe
Ribeiro B, Lopes R, Andrade PB, Seabra RM, Gonçalves RF, Baptista P, Quelhas I, Valentão P
Food Chem., 110, 47-56, 2008
Inflorescences of Brassicacea species as source of bioactive compounds: a comparative study
Sousa C, Taveira M, Valentão P, Fernandes F, Pereira JÁ, Estevinho L, Bento A, Ferreres F, Seabra RM, Andrade PB
Food Chem., 110, 953-961, 2008
Leucopaxillus giganteus mycelium: effect of nitrogen source on organic acids and alkaloids
Ribeiro B, Andrade PB, Baptista P, Barros L, Ferreira ICFR, Seabra RM, Valentão P.
J. Agric. Food Chem. 56, 4769-4774, 2008
Organic acids composition of Cydonia oblonga Miller leaf
Oliveira AP, Pereira JA, Andrade PB, Valentão P, Seabra RM, Silva B.M.
Food Chem. 111, 393-399, 2008
Targeted metabolite analysis and antioxidant potential of Rumex induratus.
Guerra, L.; Pereira, C.; Andrade, P.B.; Rodrigues, M. A.; Ferreres, F.; Guedes de Pinho, P.; Seabra, R.M.; Valentão, P.
J. Agric. Food Chem. 56, 8184-8194, 2008
Free amino acids of tronchuda cabbage (Brassica oleracea L. var. costata DC): influence of leave position (internal or external) and collection time.
Oliveira, A.P.; Pereira, D.M.; Andrade, P.B.; Valentão, P.; Sousa, C.; Pereira, J.A.; Bento, A.; Rodrigues, M. A.; Seabra, R.M.; Silva, B.M.
J. Agric. Food Chem. 56, 5216-5221, 2008
Assessing the antioxidative properties and chemical composition of Linaria vulgaris infusion.
Vrchovská, V.; Spilková, J.; Valentão, P.; Sousa, C.; Andrade, P.B.; Seabra, R.M.
Nat. Prod. Res. 22, 735-746, 2008
Do cultivar, geographical location and crop season influence phenolic profile of walnut leaves?
Amaral, J.S.; Valentão, P.; Andrade, P.B.; Martins, R.C.; Seabra, R.M.
Molecules. 13, 1321-1332, 2008
Relevant principal component analysis applied to the characterization of Portuguese heather honey.
Martins, R.C.; Lopes, V.V.; Valentão, P.; Carvalho, J.C.M.F.; Isabel, P.; Amaral, M.T.; Batista, M.T.; Andrade, P.B.; Silva, B.M.
Nat. Prod. Res., 22, 1560-1582, 2008
Recent trends in high throughput analysis and antioxidant potential screening for phenolics.
Andrade, P.B.; Pereira, D.M.; Ferreres, F.; Valentão, P.
Curr. Pharm. Anal., 4, 137-150, 2008
In vivo skin irritation potential of a Castanea sativa (chestnut) leaf extract, a putative natural antioxidant for topical application.
Almeida, I.F.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Pereira, T.M.; Amaral, M.H.; Costa, P.C.; Bahia, M.F.
Basic Clin. Pharmacol. Toxicol., 103, 461-467, 2008
Comparative study on free amino acids composition of wild edible mushroom species.
Ribeiro, B.; Andrade, P.B.; Silva, B.M.; Baptista, P.; Seabra, R.M.; Valentão, P. J.
Agric. Food Chem., 56, 10973-10979, 2008
HPLC-DAD of phenolics in bryophytes Lunularia cruciata, Brachytheciastrum velutinum and Kindbergia praelonga.
Jocković, N.; Andrade, P.B.; Valentão, P.; Sabovljević, M. J.
Serb. Chem. Soc., 73, 1161-1167, 2008

2007

New C-deoxyhexosyl flavones and antioxidant properties of Passiflora edulis leaf extract
Ferreres F, Sousa C, Valentão P, Andrade PB, Seabra RM, Gil-Izquierdo A.
J Agric Food Chem, 55:1087-93, 2007
New C-deoxyhexosyl flavones and antioxidant properties of Passiflora edulis leaf extract.
Ferreres, F.; Sousa, C.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Gil-Izquierdo, Á.
J. Agric. Food Chem. 55, 10187-10193, 2007
Solid-phase extraction versus matrix solid-phase dispersion: application to white grapes
Dopico-Garcia MS, Valentão P, Jagodziñska A, Klepczyñska J, Guerra L, Andrade PB, Seabra RM.
Talanta, 74: 20-31, 2007
Screening of antioxidant compounds during sprouting of Brassica oleracea L. var costata DC
Sousa C, Lopes G, Pereira D, Taveira M, Valentão P, Seabra RM, Pereira JA, Baptista P, Ferreres F, Andrade PB.
Combinatorial Chemistry & High Throughput Screening, 10: 377-386, 2007
Experimental design for extraction and quantification of phenolic compounds and organic acids in white “Vinho Verde” grapes.
Dopico-García MS, Valentão P, Guerra L, Andrade PB, Seabra RM
Anal. Chim. Acta , 583: 15-22, 2007
Walnut (Juglans regia L) leaves: phenolic compounds, antibacterial activity and antioxidant potential of different cultivars
Pereira JA, Oliveira I, Sousa A, Valentão P, Andrade PB, Ferreira ICFR, Ferreres F, Bento A, Seabra RM, Estevinho L.
Food and Chemical Toxicology, 45: 2287-2295, 2007
Hazel (Corylus avellana L.) leaves as a source of antimicrobial and antioxidative compounds
Oliveira I, Sousa A, Valentão P, Andrade PB, Ferreira ICFR, Ferreres F, Bento A, Seabra RM, Estevinho L, Pereira JA.
Food Chem, 105: 1018-1025, 2007
Chemical and antioxidative assessment of dietary turnip (Brassica rapa var. rapa L.)
Fermandes F, Valentão P, Sousa C, Pereira JA, Seabra RM, Andrade PB.
Food Chem, 105: 1003-1010, 2007
Beefsteak fungus Fistulina hepatica: phenolic compounds and organic acids contents and antioxidative properties.
Ribeiro, B.; Valentão, P.; Baptista, P.; Seabra, R.M.; Andrade, P.B.
Food Chem. Toxicol. 45, 1805-1813, 2007
Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-BHP induced oxidative damage
Lima C, Valentão P, Andrade PB, Seabra RM, Fernandes-Ferreira M, Pereira-Wilson C.
Chemico-Biological Interactions, 167: 107-115, 2007
Antioxidative propereties and phytochemical composition of Ballota nigra infusion
Vrchovská V, Spilková J, Valentão P, Sousa C, Andrade PB, Seabra RM.
Food Chemistry, 105: 1396-1403, 2007
Tronchuda cabbage (Brassica oleracea L. var costata DC) seeds: phytochemical characterization and antioxidant potential
Ferreres F, Sousa C, Valentão P, Seabra RM, Pereira JA, Andrade PB.
Food Chemistry 101: 549-558, 2007
Organic acids in two Portuguese chestnuts (Castanea sativa Miller) varieties
Ribeiro B, Rangel J, Valentão P, Andrade PB, Pereira JA, Bölke H, Seabra RM.
Food Chemistry 100: 504-508, 2007
Infuence of Dekkera bruxellensis on the contents of anthocyanins, organic acids and volatile phenols of Dão red wine
Valentão P, Seabra RM, Lopes G, Silva LR, Martins V, Trujillo ME, Velázquez E, Andrade PB.
Food Chemistry 100: 64–70, 2007
Homo-monoterpenic compounds as chemical markers for Cydonia oblonga Miller
Sousa C, Silva B, Andrade PB, Valentão P, Silva A, Ferreres F, Seabra RM, Ferreira MA
Food Chemistry 100: 331–338, 2007
HPLC determination of free amino acids profile of Dão red wine: effect of Dekkera bruxellensis contamination
Silva B, Silva L, Valentão P, Seabra RM, Andrade PB, Trujillo ME, Velázquez E.
J. Liq Chromatography & Rel Technol, 30: 1371-1383, 2007

2006

Phenolics and antimicrobial activity of traditional stoned table olives ‘alcaparra’.
Sousa, A.; Ferreira, I.C.F.R.; Calhelha, R.; Andrade, P.B.; Valentão, P.; Seabra, R.; Estevinho, L.; Bento, A.; Pereira, J.A.
Bioorg. Med. Chem. 14, 8533-8538, 2006
Rumex induratus leaves: an interesting dietary source of potential bioactive compounds.
Ferreres, F.; Ribeiro, V.; Gil Izquierdo, A.; Rodrigues, M.A.; Seabra, R.M.; Andrade, P.B.; Valentão, P.
J. Agric. Food Chem. 54, 5782-5789, 2006
Contents of carboxylic acids and two phenolics and antioxidant activity of dried Portuguese wild edible mushrooms
Ribeiro B, Rangel J, Valentão P, Baptista P, Seabra RM, Andrade PB
J. Agriculture Food Chem, 54: 8530-8537, 2006
Table olives from Portugal: phenolic compounds, antioxidant potential and antimicrobial activity
Pereira JA, Pereira A, Ferreira ICFR, Valentão P, Andrade PB, Seabra RM, Estevinho L, Bento A
J. Agriculture Food Chem, 54: 8425-8431, 2006
Chemical composition and antioxidant activity of tronchuda cabbage internal leaves
Ferreres F, Sousa C, Vrchovská V, Valentão P, Pereira JA, Seabra RM, Andrade PB
Eur Food Res Technol, 222: 88-98, 2006
Antioxidative properties of tronchuda cabbage (Brassica oleraceae L. var costata DC) external leaves against DPPH, superoxide radical, hydroxyl radical and hypochlorous acid
Vrchovská V, Sousa C, Valentão P, Ferreres F, Pereira JA, Seabra RM, Andrade PB
Food Chemistry, 98: 416-425, 2006

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